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Miller-Deiker syndrome — a chromosomal abnormality resulting in a characteristic facial appearance and the absence of the grooves on the surface of the brain (see lissencephaly). Affected individuals are severely mentally retarded … The new mediacal dictionary
Lissencephaly — A brain malformation characterized by microcephaly and the lack of normal convolutions (folds) in the brain. Lissencephaly literally means smooth brain. It is caused by defective neuronal migration, a defect in the process in which nerve cells… … Medical dictionary
lissencephaly — smooth brain; n. a condition in which the brain develops abnormally – it has no grooves on the outside, large ventricles, and generally is smaller than it should be. Lissencephaly causes severe mental retardation and failure to thrive. See also:… … The new mediacal dictionary
