zalcitabine

zalcitabine
zal·cit·a·bine zal-'sit-ə-.bēn, -.bīn n DDC

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(ddC)
n.
a drug, similar to didanosine, that is used to prolong the lives of patients with AIDS and HIV infection. It is administered by mouth. Possible side-effects include reversible nerve damage, ulceration of the gullet, skin rashes, severe pancreatitis, nausea, vomiting, and headache. Trade name: Hivid.

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zal·ci·ta·bine (zal-siґtə-bēn) [USP] 2′3′-dideoxycytidine, a nucleoside analogue of 2′-deoxycytidine; an antiretroviral agent that is converted intracellularly into the active metabolite dideoxycytidine 5′-triphosphate, which inhibits the action of reverse transcriptase and so inhibits viral replication; used in the treatment of human immunodeficiency virus (HIV) infection, administered orally. Formerly called dideoxycytidine (ddC).

Medical dictionary. 2011.

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Look at other dictionaries:

  • Zalcitabine — Systematic (IUPAC) name 4 amino 1 ((2R,5S) 5 (hydroxymethyl)tetrahydrofuran 2 yl)pyrimidin 2(1H) one Clinical data AHFS/Drugs.com …   Wikipedia

  • Zalcitabine — Structure chimique de la zalcitabine Général Nom IUPAC L 2 ,3 didéoxycytidine …   Wikipédia en Français

  • zalcitabine — noun Etymology: origin unknown Date: 1991 ddC …   New Collegiate Dictionary

  • zalcitabine — zal·ci·ta·bine (zălʹsĭ tə bīn ) n. See DDC.   [zal (perhaps alteration of (de)s variant of de + alcohol from the missing hydroxyl groups of cytidine) + citabine(alteration of cytidine).] * * * …   Universalium

  • zalcitabine — noun The compound 2 3 dideoxycytidine, a nucleoside analog reverse transcriptase inhibitor, formerly used in antiretroviral therapy Syn: dideoxycytidine, ddC …   Wiktionary

  • zalcitabine — zal·cit·a·bine …   English syllables

  • zalcitabine — ddC; n. a drug, similar to didanosine, that is used to prolong the lives of patients with AIDS and HIV infection. It is administered by mouth, in combination with other antiretroviral drugs. Possible side effects include peripheral neuropathy,… …   The new mediacal dictionary

  • zalcitabine — noun an antiviral drug used to combat HIV infection • Syn: ↑dideoxycytosine, ↑ddC, ↑DDC • Hypernyms: ↑antiviral, ↑antiviral agent, ↑antiviral drug …   Useful english dictionary

  • ddC — zalcitabine …   The new mediacal dictionary

  • 7481-89-2 — Zalcitabine Zalcitabine Structure chimique de la zalcitabine Général Nom IUPAC L 2 ,3 didéoxycytidi …   Wikipédia en Français

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