Wiskott-Aldrich syndrome

Wiskott-Aldrich syndrome
Wis·kott-Al·drich syndrome 'vis-.kät-'ȯl-.drich- n an inherited usu. fatal childhood immunodeficiency disease characterized esp. by thrombocytopenia, leukopenia, recurrent infections, eczema, and abnormal bleeding
Wis·kott 'vis-.kȯt Alfred (1898-1978)
German pediatrician. A professor of pediatrics in Munich, Wiskott wrote on diseases of the respiratory system and on the pathogenesis, clinical treatment, and classification of pneumonias in early childhood.
Aldrich Robert Anderson (1917-1998)
American pediatrician. Aldrich held professorships in pediatrics at the medical schools of the University of Oregon and the University of Washington. Later he was professor of preventive medicine and comprehensive health care at the University of Colorado. His areas of research included the biochemistry of bilirubin and porphyrins, the mechanism of heme synthesis, and inborn errors of metabolism.

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an X-linked immunodeficiency syndrome characterized by eczema, thrombocytopenia, and recurrent pyogenic infection. Patients cannot produce antibodies to polysaccharide antigens and have increased susceptibility to infection with encapsulated bacteria (Haemophilus influenzae, meningococcus, pneumococcus). Typically IgM is low, IgA and IgE are elevated, and there is anergy of the skin. Many affected persons also have lymphoreticular disorders. Called also Aldrich s.

Medical dictionary. 2011.

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  • Wiskott-Aldrich syndrome — Wiskott Aldrich syndrome. См. синдром Вискотта Олдрича. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Wiskott-Aldrich syndrome — Infobox Disease Name = PAGENAME Caption = DiseasesDB = 14176 ICD10 = ICD10|D|82|0|d|80 ICD9 = ICD9|279.12 ICDO = OMIM = 301000 MedlinePlus = eMedicineSubj = med eMedicineTopic = 1162 eMedicine mult = eMedicine2|ped|2443 eMedicine2|derm|702 MeshID …   Wikipedia

  • Wiskott-Aldrich syndrome — An inherited immune disorder that occurs in young boys. It causes eczema (a type of skin inflammation), a decrease in the number of platelets (blood cells that help prevent bleeding), and frequent bacterial infections. People with Wiskott Aldrich …   English dictionary of cancer terms

  • Wiskott-Aldrich syndrome — a rare sex linked recessive disorder characterized by eczema, thrombocytopenia, and deficiency in the immune response (immunodeficiency). It is caused by a decrease in the amount of Wiskott Aldrich syndrome protein (WASP: a protein occurring in… …   The new mediacal dictionary

  • Wiskott-Aldrich syndrome protein — The Wiskott Aldrich Syndrome Protein (WASp) is a 502 amino acid protein that is expressed in cells of the hematopoietic system. In the inactive state, WASp exists in an auto inhibited conformation with sequences near its C terminus binding to a… …   Wikipedia

  • Wiskott-Aldrich syndrome — Thrombocytopeniawith severe immunodeficiency (both cell mediated and IgM production). Associated with increased incidence of leukaemia …   Dictionary of molecular biology

  • Wiskott-Aldrich syndrome — noun A rare X linked recessive disease characterized by eczema, thrombocytopenia, immune deficiency, and bloody diarrhea …   Wiktionary

  • Syndrome de Wiskott-Aldrich — Référence MIM 301000 Transmission Récessive à l X Chromosome Xp11.23 p11.22 Gène WAS Empreinte parentale Non …   Wikipédia en Français

  • Syndrome de wiskott-aldrich — Autre nom Aucun Référence MIM …   Wikipédia en Français

  • Wiskott-Aldrich-Syndrom — Klassifikation nach ICD 10 D82.0 Wiskott Aldrich Syndrom Immundefekt mit Thrombozytopenie und Ekzem …   Deutsch Wikipedia

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