thi·a·zide 'thī-ə-.zīd, -zəd n any of a group of drugs used as oral diuretics esp. in the control of high blood pressure

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thi·a·zide (thiґə-zīd) any of a group of benzothiadiazene sulfonamide derivatives, typified by chlorothiazide, that act as diuretics by inhibiting the reabsorption of sodium in the proximal renal tubule and stimulating chloride excretion, with resultant increase in excretion of water. They also increase the excretion of potassium, which can cause hypokalemia requiring potassium supplementation, and some increase in bicarbonate excretion. Thiazides are used for the treatment of edema due to congestive heart failure or chronic hepatic or renal disease and, alone or in combination with other drugs, in the treatment of hypertension. Called also benzothiadiazide, benzothiadiazine, and thiadiazine.

Medical dictionary. 2011.

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  • Thiazide — Als Thiaziddiuretika wird eine Gruppe harntreibender Substanzen bezeichnet, die als Weiterentwicklung der Carboanhydrasehemmer vom Typ des Acetazolamid zu sehen sind. Chemisch handelt es sich zum einen um Weiterentwicklungen von Chlorothiazid,… …   Deutsch Wikipedia

  • -thiazide — a suffix indicating a thiazide diuretic …   Medical dictionary

  • thiazide diabetes — glucose intolerance or overt hyperglycemia induced by thiazide diuretics, which inhibit insulin secretion, possibly through thiazide induced hypokalemia …   Medical dictionary

  • thiazide diuretics — a group of synthetic compounds that cause diuresis by altering electrolyte reabsorption at the distal tubules and increase urinary excretion of sodium and chloride in approximately equal amounts; they are used to treat edema, hypertension, and… …   Medical dictionary

  • thiazide — noun Etymology: thi + diazine + dioxide Date: 1959 any of a group of drugs used as oral diuretics especially in the control of high blood pressure …   New Collegiate Dictionary

  • thiazide — /thuy euh zuyd , zid/, n. Pharm. a member of a class of diuretic substances that inhibit the reabsorption of sodium chloride in the distal convoluted tubule of the kidneys: used principally to treat hypertension. [1955 60; THI + AZIDE] * * * …   Universalium

  • thiazide — noun Any of a class of diuretic drugs based on a benzothiadiazine sulfonamide dioxide …   Wiktionary

  • thiazide — [ θʌɪəzʌɪd] noun Medicine any of a class of sulphur containing drugs that are used as diuretics and to lower the blood pressure. Origin 1950s: from elements of thio + azine + oxide …   English new terms dictionary

  • thiazide — thi·a·zide …   English syllables

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