thiazide diuretics

thiazide diuretics
a group of synthetic compounds that cause diuresis by altering electrolyte reabsorption at the distal tubules and increase urinary excretion of sodium and chloride in approximately equal amounts; they are used to treat edema, hypertension, and diabetes insipidus. The class of drugs is sometimes extended to include compounds which act like thiazide diuretics but are chemically dissimilar.

Medical dictionary. 2011.

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  • Thiazide — is a term used to describe a type of molecule [MeshName|Thiazides] and a class of diuretic. [MeshName|Thiazide+Diuretics] The members of this class of diuretics are derived from benzothiadiazine. They inhibit Na+/Cl reabsorption from the distal… …   Wikipedia

  • Thiazide — Als Thiaziddiuretika wird eine Gruppe harntreibender Substanzen bezeichnet, die als Weiterentwicklung der Carboanhydrasehemmer vom Typ des Acetazolamid zu sehen sind. Chemisch handelt es sich zum einen um Weiterentwicklungen von Chlorothiazid,… …   Deutsch Wikipedia

  • thiazide diabetes — glucose intolerance or overt hyperglycemia induced by thiazide diuretics, which inhibit insulin secretion, possibly through thiazide induced hypokalemia …   Medical dictionary

  • thiazide — thi·a·zide thī ə .zīd, zəd n any of a group of drugs used as oral diuretics esp. in the control of high blood pressure * * * thi·a·zide (thiґə zīd) any of a group of benzothiadiazene sulfonamide derivatives, typified by chlorothiazide,… …   Medical dictionary

  • thiazide — noun Etymology: thi + diazine + dioxide Date: 1959 any of a group of drugs used as oral diuretics especially in the control of high blood pressure …   New Collegiate Dictionary

  • thiazide — [ θʌɪəzʌɪd] noun Medicine any of a class of sulphur containing drugs that are used as diuretics and to lower the blood pressure. Origin 1950s: from elements of thio + azine + oxide …   English new terms dictionary

  • thiazide — noun any of a group of drugs commonly used as diuretics in the treatment of hypertension; they block the reabsorption of sodium in the kidneys • Hypernyms: ↑diuretic drug, ↑diuretic, ↑water pill • Hyponyms: ↑chlorothiazide, ↑Diuril, ↑hydroch …   Useful english dictionary

  • potassium-sparing diuretics — a class of drugs that block the exchange of sodium for potassium and hydrogen ions in the distal tubule, causing an increase in the excretion of sodium and chloride with a negligible increase in potassium excretion; used in the treatment of edema …   Medical dictionary

  • Metolazone — Systematic (IUPAC) name 7 chloro 2 methyl 4 oxo 3 o tolyl 1,2,3,4 tetrahydroquinazoline 6 sulfonamide Clinical data Trade names …   Wikipedia

  • Hydrochlorothiazide — Systematic (IUPAC) name …   Wikipedia

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