substance P

substance P
substance P n a neuropeptide that consists of 11 amino acid residues, that is widely distributed in the brain, spinal cord, and peripheral nervous system, and that acts across nerve synapses to produce prolonged postsynaptic excitation

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a peptide composed of 11 amino acids, present in nerve cells throughout the body and in special endocrine cells in the intestine. It increases the contractions of gastrointestinal smooth muscle and causes vasodilatation, and is one of the most potent vasoactive substances known. It also serves as a sensory neurotransmitter, mediating pain, touch, and temperature.

Medical dictionary. 2011.

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