sphingomyelin

sphingomyelin
sphin·go·my·elin .sfiŋ-gō-'mī-ə-lən n any of a group of crystalline phosphatides that are obtained esp. from nerve tissue and that on hydrolysis yield a fatty acid (as lignoceric acid), sphingosine, choline, and phosphoric acid

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n.
a phospholipid that contains sphingosine, a fatty acid, phosphoric acid, and choline. Sphingomyelins are found in large amounts in brain and nerve tissue.

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sphin·go·my·elin (sfing″go-miґə-lin) any of the group of sphingolipids in which the head group is phosphorylated choline, making them sphingophospholipids; they are the only phospholipids not derived from glycerol in humans. They occur in membranes, primarily in nervous tissue, and are accumulated abnormally in Niemann-Pick disease.

Medical dictionary. 2011.

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  • Sphingomyelin — Sphingomyelin(SPH) is a type of sphingolipid found in animal cell membranes, especially in the membranous myelin sheath which surrounds some nerve cell axons. It usually consists of phosphorylcholine and ceramide. In humans SPH represents 85% of… …   Wikipedia

  • Sphingomyelin — mit einem Phosphocholin als Kopfgruppe Allgemeine Strukturformel der Sphingolipide. Bei Sphingomyelinen …   Deutsch Wikipedia

  • sphingomyelin — sphingomyelin. См. сфингомиелин. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • sphingomyelin — A sphingolipid in which the head group is phosphoryl choline. A close analogue of phosphatidyl choline. In many cells the concentration of sphingomyelin and phosphatidyl choline in the plasma membrane seems to bear a reciprocal relationship …   Dictionary of molecular biology

  • Sphingomyelin phosphodiesterase 1 — Sphingomyelin phosphodiesterase 1, acid lysosomal (acid sphingomyelinase), also known as SMPD1, is a human sphingomyelin phosphodiesterase.cite web | title = Entrez Gene: SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal (acid… …   Wikipedia

  • Sphingomyelin-Phosphodiesterase — Sphingomyelinase Bezeichner Gen Namen …   Deutsch Wikipedia

  • Sphingomyelin synthase — In enzymology, a sphingomyelin synthase (EC number|2.7.8.27) is an enzyme that catalyzes the chemical reaction:a ceramide + a phosphatidylcholine ightleftharpoons a sphingomyelin + a 1,2 diacyl sn glycerolThus, the two substrates of this enzyme… …   Wikipedia

  • Sphingomyelin lipoidosis — Also called Niemann Pick disease, this is a disorder of the metabolism of a lipid (fat) called sphingomyelin that usually causes the progressive development of enlargement of the liver and spleen (hepatosplenomegaly), swollen glands… …   Medical dictionary

  • sphingomyelin phosphodiesterase — An enzyme catalyzing hydrolysis of sphingomyelin to N acylsphingosine (a ceramide) and phosphocholine; a deficiency of this enzyme is associated with type I Niemann Pick disease. SYN: sphingomyelinase. * * * sphin·g …   Medical dictionary

  • Sphingomyelin phosphodiesterase — Sphingomyelinase phosphodiesterase or simply Sphingomyelinase (SMase) is a hydrolase enzyme that is involved in sphingolipid metabolism reactions. SMase is a member of the DNase I superfamily of enzymes and is responsible for breaking… …   Wikipedia

  • sphingomyelin — /sfing goh muy euh lin/, n. Biochem. any of the class of phospholipids occurring chiefly in the brain and spinal cord, composed of phosphoric acid, choline, sphingosine, and a fatty acid. [ < NL sphingo , comb. form repr. Gk sphíngein to draw… …   Universalium

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