signet ring cell

signet ring cell
signet ring cell n a cell that has its nucleus shifted to one side by a large cytoplasmic vacuole and that occurs esp. in mucin-producing adenocarcinomas esp. of the stomach

* * *

a cell in which the nucleus has been pressed to one side by an accumulation of intracytoplasmic mucin, as in signet ring cell carcinoma and Krukenberg tumor.

Medical dictionary. 2011.

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