sickle-cell anemia

sickle-cell anemia
sickle-cell anemia n a chronic anemia that occurs in individuals (as those of African or Mediterranean descent) who are homozygous for the gene controlling hemoglobin S and that is characterized by destruction of red blood cells and by episodic blocking of blood vessels by the adherence of sickle cells to the vascular endothelium which causes the serious complications of the disease (as organ failure)

Medical dictionary. 2011.

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  • sickle-cell anemia — sickle cell anemia. См. серповидноклеточная анемия. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • sickle cell anemia — Pathol. a chronic hereditary blood disease, occurring primarily among Africans or persons of African descent, in which abnormal hemoglobin causes red blood cells to become sickle shaped and nonfunctional, characterized by enlarged spleen, chronic …   Universalium

  • Sickle cell anemia — A genetic blood disease due to the presence of an abnormal form of hemoglobin, namely hemoglobin S. Hemoglobin is the molecule in red blood cells that transports oxygen from the lungs to the farthest areas of the body. Sickle cell anemia affects… …   Medical dictionary

  • sickle cell anemia — An inherited disease in which the red blood cells have an abnormal crescent shape, block small blood vessels, and do not last as long as normal red blood cells. Sickle cell anemia is caused by a mutation (change) in one of the genes for… …   English dictionary of cancer terms

  • sickle cell anemia disease — ☆ sickle cell anemia disease n. an inherited chronic anemia found chiefly among blacks, characterized by an abnormal red blood cell (sickle cell) containing a defective form of hemoglobin that causes the cell to become sickle shaped when deprived …   Universalium

  • sickle cell anemia disease — ☆ sickle cell anemia disease n. an inherited chronic anemia found chiefly among blacks, characterized by an abnormal red blood cell (sickle cell) containing a defective form of hemoglobin that causes the cell to become sickle shaped when deprived …   English World dictionary

  • sickle cell anemia — sickle cell a nemia noun uncount a blood disease that mainly affects black people …   Usage of the words and phrases in modern English

  • sickle-cell anemia — noun a congenital form of anemia occurring mostly in blacks; characterized by abnormal blood cells having a crescent shape • Syn: ↑sickle cell anaemia, ↑sickle cell disease, ↑crescent cell anemia, ↑crescent cell anaemia, ↑drepanocytic anemia,… …   Useful english dictionary

  • sickle-cell anemia — noun Date: 1922 a chronic inherited anemia that occurs primarily in individuals of African, Mediterranean, or southwest Asian ancestry who are homozygous for the gene controlling hemoglobin S and that is characterized especially by episodic… …   New Collegiate Dictionary

  • sickle-cell anemia — noun A disease characterized by sickle shaped red blood cells. Syn: sickle cell disease …   Wiktionary

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