Rubin test

Ru·bin test 'rü-bən- n a test to determine the patency or occlusion of the fallopian tubes by insufflating them with carbon dioxide by transuterine injection

Rubin Isidor Clinton (1883-1958)

American gynecologist. Rubin's early researches dealt with the pathology of cancer of the cervix of the uterus. He turned toward the study of sterility, and after several years he successfully developed the first test for determining the patency of the fallopian tubes. The test, now known as the Rubin test, was first performed in 1919, and a report was published in 1920. The author of three major gynecological texts and over 132 articles, Rubin was widely regarded as the foremost researcher of fertility in the 20th century.

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1. (for patency of uterine tubes) transuterine insufflation is done with carbon dioxide. If the tubes are patent the gas enters the peritoneal cavity and may be demonstrated by the fluoroscope or radiograph. This subphrenic pneumoperitoneum may cause pain in one or both shoulders of the patient. If the manometer registers not over 100 mm Hg the tubes are patent; if between 120 and 130, there may be stenosis or stricture, but not complete occlusion; if it rises to 200, the tubes are completely occluded. 2. (for avian leukosis viruses in egg-culture vaccines) if the viruses are present, they induce a cellular resistance to Rous sarcoma viruses subsequently inoculated (resistance-inducing factor). Called also RIF t.