reverse transcriptase inhibitor

reverse transcriptase inhibitor
reverse transcriptase inhibitor n an agent that inhibits the activity of a reverse transcriptase esp a drug (as AZT) that acts by inhibiting retroviral reverse transcription

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a substance that blocks activity of the reverse transcriptase of a retrovirus and is used as an antiretroviral agent. Some are nucleosides or nucleoside analogues, and those that are not are therefore often called non-nucleoside reverse transcriptase inhibitors.

Medical dictionary. 2011.

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  • reverse transcriptase inhibitor — noun an antiviral drug that inhibits the action of reverse transcriptase in retroviruses such as HIV • Hypernyms: ↑antiviral, ↑antiviral agent, ↑antiviral drug • Hyponyms: ↑non nucleoside reverse transcriptase inhibitor, ↑NNRTI, ↑nucl …   Useful english dictionary

  • Reverse-transcriptase inhibitor — Reverse transcriptase inhibitors (RTIs) are a class of antiretroviral drug used to treat HIV infection, tumors,[1] and cancer.[2] RTIs inhibit activity of reverse transcriptase, a viral DNA polymerase enzyme that retroviruses need to reproduce.… …   Wikipedia

  • Reverse transcriptase inhibitor — Reverse transcriptase inhibitors (RTIs) are a class of antiretroviral drug used to treat HIV infection, tumors [ [http://jcem.endojournals.org/cgi/content/full/90/10/5663/F1 Reverse Transcriptase Inhibitors Down Regulate Cell Proliferation in… …   Wikipedia

  • Nucleoside Reverse Transcriptase Inhibitor — Reverse Transkriptase des HIV 1 Nukleosidische Reverse Transkriptase Inhibitoren (engl. Nucleoside Reverse Transcriptase Inhibitors, NRTI) sind Arzneistoffe aus der Gruppe der Virostatika. Es handelt sich um Nukleosid Analoga, die den natürlichen …   Deutsch Wikipedia

  • non-nucleoside reverse transcriptase inhibitor — noun an antiviral drug used against HIV; binds directly to reverse transcriptase and prevents RNA conversion to DNA; often used in combination with other drugs • Syn: ↑NNRTI • Hypernyms: ↑reverse transcriptase inhibitor • Hyponyms: ↑delavirdine,… …   Useful english dictionary

  • nucleoside reverse transcriptase inhibitor — noun an antiviral drug used against HIV; is incorporated into the DNA of the virus and stops the building process; results in incomplete DNA that cannot create a new virus; often used in combination with other drugs • Syn: ↑NRTI • Hypernyms:… …   Useful english dictionary

  • non-nucleoside reverse transcriptase inhibitor — (NNRTI) see reverse transcriptase i …   Medical dictionary

  • Reverse transcriptase — Protbox Name=Reverse Transcriptase Photo=1HMV.png|250px Caption=3D model of HIV reverse transcriptase HGNCid = Symbol = AltSymbols = Chromosome = Arm = Band = LocusSupplementaryData = Gene= Gene type= Protein length= Molecular weight= Structure=… …   Wikipedia

  • Discovery and development of nucleoside and nucleotide reverse-transcriptase inhibitors — (NRTIs and NtRTIs) began in the 1980s when the AIDS epidemic hit Western societies. NRTIs inhibit the reverse transcriptase (RT), an enzyme that controls the replication of the genetic material of the human immunodeficiency virus (HIV). The first …   Wikipedia

  • Discovery and development of non-nucleoside reverse-transcriptase inhibitors — Non nucleoside reverse transcriptase inhibitors (NNRTIs) are antiretroviral drugs used in the treatment of human immunodeficiency virus (HIV). NNRTIs inhibit reverse transcriptase (RT), an enzyme that controls the replication of the genetic… …   Wikipedia

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