- quin·o·lone 'kwin-ə-.lōn n any of a class of synthetic antibacterial drugs that are derivatives of hydroxylated quinolines and inhibit the replication of bacterial DNA esp FLUOROQUINOLONE
* * *n.one of a group of chemically related synthetic antibiotics that includes ciprofloxacin, nalidixic acid, and ofloxacin. These drugs act by inactivating an enzyme, DNA gyrase, that is necessary for replication of the microorganisms and are often useful for treating infections with organisms that have become resistant to other antibiotics. They are administered by mouth. Possible side-effects include nausea, vomiting, diarrhoea, abdominal pain, headache, dizziness, and itching. Confusion, joint pains, skin troubles, and tendinitis occasionally occur.
* * *quin·o·lone (kwinґo-lōn) any of a group of synthetic antibacterial agents that includes nalidixic acid, cinoxacin, rosoxacin, and the fluoroquinolones.
Medical dictionary. 2011.