proteoglycan

proteoglycan
pro·teo·gly·can .prōt-ē-ə-'glī-.kan n any of a class of glycoproteins of high molecular weight that are found in the extracellular matrix of connective tissue, are made up mostly of carbohydrate consisting of various polysaccharide side chains linked to a protein, and resemble polysaccharides rather than proteins in their properties

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pro·teo·gly·can (pro″te-o-gliґkan) any of a group of polysaccharide-protein conjugates occurring primarily in the matrix of connective tissue and cartilage, composed mainly of polysaccharide chains, particularly glycosaminoglycans, as well as minor protein components. Individual subunits consist of a polypeptide backbone to which many glycosaminoglycan chains are covalently linked; large aggregates resembling bottle brushes are formed when many such subunits are attached via small proteins to long hyaluronan chains.

Medical dictionary. 2011.

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Look at other dictionaries:

  • Proteoglycan — Proteoglycans represent a special class of glycoproteins that are heavily glycosylated. They consist of a core protein with one or more covalently attached glycosaminoglycan (GAG) chain(s). These glycosaminoglycan chains are long, linear… …   Wikipedia

  • proteoglycan — noun Etymology: International Scientific Vocabulary Date: 1968 any of a class of glycoproteins of high molecular weight that are found especially in the extracellular matrix of connective tissue …   New Collegiate Dictionary

  • Proteoglycan — Proteoglykane sind ein wichtiger Bestandteil der Extrazellulären Matrix, sind aber auch an der Zelloberfläche und in intrazellulären sekretorischen Granula lokalisiert. Proteoglykane bilden eine Klasse von besonders stark glykosylierten… …   Deutsch Wikipedia

  • proteoglycan — A high molecular weight complex of protein and polysaccharide, characteristic of structural tissues of vertebrates, such as bone and cartilage, but also present on cell surfaces. Important in determining viscoelastic properties of joints and… …   Dictionary of molecular biology

  • proteoglycan — /proh tee oh gluy kan/, n. Biochem. a macromolecule composed of a polysaccharide joined to a polypeptide and forming the ground substance of connective tissue. [1969; PROTE(IN) + O + GLYC + an, var. of ANE] * * * …   Universalium

  • proteoglycan — noun Any of many glycoproteins that have heteropolysaccharide side chains …   Wiktionary

  • proteoglycan I — SYN: biglycan …   Medical dictionary

  • proteoglycan — [ˌprəʊtɪəʊ glʌɪkan] noun Biochemistry a compound consisting of a protein bonded to mucopolysaccharide groups, present especially in connective tissue …   English new terms dictionary

  • proteoglycan — proteo·glycan …   English syllables

  • proteoglycan — A molecule that contains both protein and glycosaminoglycans, which are a type of polysaccharide. Proteoglycans are found in cartilage and other connective tissues …   English dictionary of cancer terms

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