platelet-activating factor
- platelet-activating factor
plate·let-ac·ti·vat·ing factor -.ak-tə-.vāt-iŋ- n phospholipid that is produced esp. by mast cells and basophils, causes the aggregation of blood platelets and the release of blood-platelet substances (as histamine or serotonin),
and is a mediator of inflammation (as in
asthma)
abbr. PAF
* * *
(PAF) a substance released by basophils and mast cells in immediate hypersensitivity reactions and macrophages and neutrophils in other inflammatory responses; it is an extremely potent mediator of bronchoconstriction and of the platelet aggregation and release reactions. It differs from other known biochemical mediators in being a phospholipid. Called also PAF-acether or AGEPC (acetyl glyceryl ether phosphoryl choline).
Medical dictionary.
2011.
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Platelet-activating factor — Identifiers CAS number 74389 68 7 … Wikipedia
Platelet-activating factor receptor — Identifiers Symbols PTAFR; PAFR External IDs OMI … Wikipedia
Platelet-activating factor acetyltransferase — In enzymology, a platelet activating factor acetyltransferase (EC number|2.3.1.149) is an enzyme that catalyzes the chemical reaction:1 alkyl 2 acetyl sn glycero 3 phosphocholine + 1 organyl 2 lyso sn glycero 3 phospholipid ightleftharpoons 1… … Wikipedia
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Platelet Activating Factor — Facteur d activation plaquettaire Le facteur d activation plaquettaire (ou PAF) est un glycérophospholipide (PL) contenant une liaison éther avec une chaîne grasse alkyle en position sn 1 du squelette de glycérol et un acétyle en position sn 2.… … Wikipédia en Français
Platelet-activating Factor — Plate|let ac|ti|va|ting Fac|tor [ pleɪtlətæktɪveɪtɪŋ fæktə[r]; engl. = plättchenaktivierender Faktor], der; s: svw. ↑ PAF … Universal-Lexikon
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factor — 1. One of the contributing causes in any action. 2. One of the components that by multiplication makes up a number or expression. 3. SYN: gene. 4. A vitamin or other essential element. 5. An event, characteristic, or other definable entity that … Medical dictionary
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