ornithine decarboxylase

ornithine decarboxylase
ornithine decarboxylase n an enzyme that catalyzes the decarboxylation of ornithine to form putrescine

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or·ni·thine de·car·box·y·lase (orґnĭ-thēn de″kahr-bokґsə-lās) [EC 4.1.1.17] a cytosolic enzyme of the lyase class that catalyzes the decarboxylation of ornithine to form putrescine; the reaction occurs in the conversion of arginine to spermine and spermidine and in the synthesis of γ-aminobutyric acid via putrescine. The enzyme requires pyridoxal phosphate as a cofactor and is concentrated in rapidly proliferating cells.

Medical dictionary. 2011.

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