malignant transformation

malignant transformation
malignant transformation n the transformation that a cell undergoes to become a rapidly dividing tumor-producing cell also the transformation of a mass of cells or a tissue into a rapidly growing tumor <malignant transformation of certain warts>

Medical dictionary. 2011.

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  • Malignant transformation — In genetics, transformation is also used to describe the incorporation of foreign DNA by bacteria. Malignant transformation is the process by which cells acquire the properties of cancer. This may occur as a primary process in normal tissue, or… …   Wikipedia

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  • Transformation (genetics) — An unrelated process called malignant transformation occurs in the progression of cancer. In molecular biology transformation is the genetic alteration of a cell resulting from the direct uptake, incorporation and expression of exogenous genetic… …   Wikipedia

  • transformation — 1. SYN: metamorphosis. 2. A change of one tissue into another, as cartilage into bone. 3. In metals, a change in phase and physical properties in the solid state caused by heat …   Medical dictionary

  • malignant peripheral nerve sheath tumor — a malignant type of schwannoma whose appearance is superficially similar to that of a fibrosarcoma; it may occur in association with neurofibromatosis that is undergoing malignant transformation. Called also malignant schwannoma,… …   Medical dictionary

  • malignant histiocytosis — a rare type of histiocytosis found accompanying malignancies such as acute myelogenous leukemia; it may be a malignant transformation of stem cells of the monocyte series. It usually affects children or young adults and has a poor prognosis …   Medical dictionary

  • viral transformation — Malignant transformation of an animal cell in culture, induced by a virus …   Dictionary of molecular biology

  • transformation — n. 1 the act or an instance of transforming; the state of being transformed. 2 Zool. a change of form at metamorphosis, esp. of insects, amphibia, etc. 3 the induced or spontaneous change of one element into another. 4 Math. a change from one… …   Useful english dictionary

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