Tumor, Wilms

Tumor, Wilms
A malignant tumor of the kidney in young children. It is also known as nephroblastoma. Wilms tumor is the most common kidney cancer in children and one the most important malignancies in childhood. About 450 new cases of Wilms tumor are diagnosed each year in the U.S. Wilms tumor has a characteristic appearance under the microscope. (It is composed of small spindle cells and other types of tissue, including kidney tubules and glomeruli, and muscle and cartilage.) The treatment of Wilms tumor exemplifies the effectiveness of combining surgery, chemotherapy, and radiation in the treatment of children with cancer. The mortality (death) rate from Wilms tumor was over 60% in the 1950s. However, the survival rate (without recurrence) 2 years after diagnosis now exceeds 90%. Risk factors for the recurrence of Wilms tumor — when it recurs, it tends to stay in the locality not far where it started — include an advanced stage of the tumor (particularly if there is involvement of the lymph nodes near the aorta), an unfavorable microscopic appearance of the tumor, and spillage of tumor cells at the time of surgery. The name Wilms is neither plural nor possessive. It is the family name of Max Wilms, a German surgeon (1867-1918) who described the tumor.

Medical dictionary. 2011.

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  • Wilms' tumor — Classification and external resources Cut section showing two halves of a nephroblastoma specimen. Note the prominent septa subdividing the sectioned surface and the protrusion of tumor into the renal pelvis, resembling botryoid rhabdomyosarcoma …   Wikipedia

  • Tumor de Wilms — Células tumorales (las células estrelladas) de un nefroblastoma. Microscopía electrónica. Clasificación y recursos externos CIE 10 …   Wikipedia Español

  • Wilms-Tumor — …   Deutsch Wikipedia

  • Wilms' tumor — also Wilms s tumor vilmz (əz ) n a malignant tumor of the kidney that primarily affects children and is made up of embryonic elements called also nephroblastoma Wilms Max (1867 1918) German surgeon. Wilms held professorships at Basel, Switzerland …   Medical dictionary

  • Wilms-Tumor-Protein — Masse/Länge Primärstruktur 449 Aminosäuren …   Deutsch Wikipedia

  • tumor de Wilms — tumor maligno del riñón en la primera infancia, de muy rápido crecimiento, constituído por elementos embrionarios y en el que se observan metástasis a distancia muy frecuentemente. Nefroblastoma imagen patológica [véase… …   Diccionario médico

  • Wilms tumor — or Wilms s tumor «vihlmz or VIHLM zihz», a painless, but malignant tumor in the kidneys, usually in children. ╂[< Max Wilms, 1867 1918, a German surgeon, who described it] …   Useful english dictionary

  • Wilms — bezeichnet ein Nephroblastom (Wilms Tumor), benannt nach Max Wilms Wilms ist der Name von: André Wilms (* 1947), französischer Schauspieler Andreas Wilms (1494–1557), deutscher Kirchenrechtler und Reformator Bernd Wilms (* 1940), deutscher… …   Deutsch Wikipedia

  • Wilms'tumor — (wĭlmz) n. A malignant tumor of the kidney that is associated with certain genetic abnormalities and chiefly affects young children. Also called nephroblastoma.   [After MaxWilms (1867 1918), German surgeon.] * * * …   Universalium

  • Wilms tumor — Wilms tumor. См. опухоль Вильмса. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

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