Letterer-Siwe disease

Letterer-Siwe disease
Let·ter·er-Si·we disease 'let-ər-ər-'sē-və- n an acute disease of children characterized by fever, hemorrhages, and other evidences of a disturbance in the reticuloendothelial system and by severe bone lesions esp. of the skull
Letterer Erich (1895-1982)
German physician. Letterer first described Letterer-Siwe disease in 1924. The author of several textbooks on pathology, he described the disease from the viewpoint of a pathologist.
Siwe Sture August (1897-1966)
Swedish pediatrician. Siwe presented another, independent description of Letterer-Siwe disease in 1933, this time from the clinical point of view.

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E. Letterer (20th century) and S. A. Siwe (1897-1966), German physicians

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a Langerhans cell histiocytosis of early childhood, of autosomal recessive inheritance, characterized by cutaneous lesions resembling seborrheic dermatitis, hemorrhagic tendency, hepatosplenomegaly with lymph node enlargement, and progressive anemia. If untreated it is rapidly fatal. Called also L-S d. and acute disseminated Langerhans cell histiocytosis.

Medical dictionary. 2011.

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  • Letterer-Siwe disease — DiseaseDisorder infobox Name = PAGENAME ICD10 = ICD10|C|96|0|c|81 ICD9 = ICD9|202.5 ICDO = Caption = OMIM = 246400 MedlinePlus = eMedicineSubj = eMedicineTopic = DiseasesDB = 5906 MeshID = D006646 | Letterer Siwe disease is a type of… …   Wikipedia

  • letterer-siwe disease — ˈled.ərə(r)ˈzēvə noun Usage: usually capitalized L&S Etymology: after Erich Letterer b1895 German pathologist and Sture A. Siwe b1897 pediatrican and professor in Sweden, who first described it : an acute disease of children characterized by… …   Useful english dictionary

  • Letterer-Siwe disease — see Langerhans cell histiocytosis [Letterer (20th century) and S. A. Siwe (1897–1966), German physicians] …   The new mediacal dictionary

  • enfermedad de Letterer-Siwe — Eng. Letterer Siwe disease Variedad de histiocitosis X de aparición en el primer año de vida caracterizada por afectación multisistémica y mal pronóstico, apreciándose hepatoesplenomegalia, lesiones eczematosas, púrpura, linfadenopatías,… …   Diccionario de oftalmología

  • Болезнь Леттерера-Сиве (Letterer-Siwe Disease) — см. Ретикулоэндотеяиоз. Источник: Медицинский словарь …   Медицинские термины

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