lepra reaction

lepra reaction
lepra reaction n one of the acute episodes of chills and fever, malaise, and skin eruption occurring in the chronic course of leprosy

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an aggravation of lumps on the skin caused by leprosy, accompanied by fever and malaise.

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an acute or subacute hypersensitivity reaction occurring either during the course of antileprosy treatment or in untreated cases of leprosy. There are two types, now often called type 1 and type 2. Type 1 includes the reversal or upgrading reaction and the downgrading reaction, which are delayed hypersensitivity reactions. Type 2 is erythema nodosum leprosum, a type III hypersensitivity reaction.

Medical dictionary. 2011.

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  • lepra reaction — an aggravation of lumps on the skin caused by leprosy, accompanied by fever and malaise …   The new mediacal dictionary

  • lepra reaction — noun : one of the acute episodes of chills and fever, malaise, and skin eruption occurring in the chronic course of leprosy …   Useful english dictionary

  • Реакция Лепры (Lepra Reaction) — увеличение кожных образований, возникающее при лепре и сопровождающееся повышением температуры и общим недомоганием. Источник: Медицинский словарь …   Медицинские термины

  • lepra — lep·ra lep rə n LEPROSY * * * lep·ra (lepґrə) [Gr. lepra leprosy, which makes the skin scaly] leprosy. See also under reaction …   Medical dictionary

  • downgrading reaction — a type 1 lepra reaction, similar in appearance to the reversal reaction (upgrading reaction), but representing a deterioration in the immune response to Mycobacterium leprae, worsening of clinical symptoms, and an increased index of M. leprae in… …   Medical dictionary

  • reversal reaction — a type 1 lepra reaction usually occurring during chemotherapy in borderline leprosy. It is a type of delayed hypersensitivity reaction with “upgrading” of cell mediated immunity to Mycobacterium leprae; this process tends to move the disease… …   Medical dictionary

  • РЕАКЦИЯ ЛЕПРЫ — (lepra reaction) увеличение кожных образований, возникающее при лепре и сопровождающееся повышением температуры и общим недомоганием …   Толковый словарь по медицине

  • erythema nodosum leprosum — the type 1 kind of lepra reaction; it resembles an Arthus reaction, and usually occurs during chemotherapy for lepromatous or borderline lepromatous leprosy, although occasionally it appears spontaneously. It is usually characterized by… …   Medical dictionary

  • Diffuse leprosy of Lucio and Latapí — The diffuse leprosy of Lucio and Lapatí, also known as diffuse lepromatous leprosy or pretty leprosy is a clinical variety of lepromatous leprosy. It was first described by Lucio and Alvarado in 1852 and re identified by Latapí in 1936. It is… …   Wikipedia

  • Mosuke Murata — (村田 茂助, Murata Mosuke?) is a Japanese dermatologist and was the designator of erythema nodosum leprosum (ENL)(1912), the type 2 lepra reaction. Contents 1 Life and works …   Wikipedia

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