Bacterial artificial chromosome

Bacterial artificial chromosome
A laboratory creation involving an artificially constructed chromosome in which medium-sized segments of DNA (100,000 to 300,000 bases in length) that come from another species are cloned into bacteria. Once the foreign DNA has been cloned into the bacteria's chromosome, many copies of it can be made (amplified) and sequenced. Bacterial artificial chromosome is abbreviated BAC.

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(BAC) a genetically engineered cloning vector based on a bacterial plasmid; it can accept large (approximately 300 kb) inserts of foreign DNA and be introduced into and propagated in bacteria; used for cloning, mapping, and sequencing.

Medical dictionary. 2011.

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Look at other dictionaries:

  • Bacterial Artificial Chromosome — Chromosome artificiel bactérien Pour les articles homonymes, voir BAC. Un chromosome bactérien artificiel CBA ou BAC (pour Bacterial Artificial Chromosome), est un vecteur bactérien conçu pour la cartographie et l analyse des génomes complexes… …   Wikipédia en Français

  • Bacterial artificial chromosome — Chromosome artificiel bactérien Pour les articles homonymes, voir BAC. Un chromosome bactérien artificiel CBA ou BAC (pour Bacterial Artificial Chromosome), est un vecteur bactérien conçu pour la cartographie et l analyse des génomes complexes… …   Wikipédia en Français

  • Bacterial artificial chromosome — A bacterial artificial chromosome (BAC) is a DNA construct, based on a functional fertility plasmid (or F plasmid), used for transforming and cloning in bacteria, usually E. coli.[1][2] F plasmids play a crucial role because they contain… …   Wikipedia

  • Bacterial Artificial Chromosome — BAC (engl. Bacterial Artificial Chromosome) ist ein künstliches Chromosom, das aus dem single copy F Plasmid des Bakteriums Escherichia coli entwickelt wurde. BACs dienen als Vektoren und erlauben im Gegensatz zu den Cosmiden und Plasmiden die… …   Deutsch Wikipedia

  • bacterial artificial chromosome — A plasmid vector that can be used to clone large inserts of DNA (up to 500 kb). See: yeast artificial chromosome …   Glossary of Biotechnology

  • bacterial artificial chromosome — Method of construction of genomic library, in which the vector contains sites necessary for the DNA to be handled and replicated as a bacterial chromosome. Like YACs, this allows clones to contain very large pieces of DNA (around 200 kb), so… …   Dictionary of molecular biology

  • bacterial artificial chromosome — (BAC) A cloning vector constructed from the E. coli F factor plasmid that is used to clone foreign DNA fragments in E. coli …   Dictionary of microbiology

  • Artificial chromosome — may refer to: * Yeast artificial chromosome * Bacterial artificial chromosome * Human artificial chromosome …   Wikipedia

  • Human artificial chromosome — A human artificial chromosome (HAC) is a microchromosome that can act as a new chromosome in a population of human cells. That is, instead of 46 chromosomes, the cell could have 47 with the 47th being very small, roughly 6 10 megabases in size,… …   Wikipedia

  • P1-derived artificial chromosome — The P1 derived artificial chromosome are DNA constructs that are derived from the DNA of P1 bacteriophage. They can carry large amounts (about 100 300 kilobases) of other sequences for a variety of bioengineering purposes. It is one type of… …   Wikipedia

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