- Krebs cycle
- Krebs cycle 'krebz- n a sequence of reactions in the living organism in which oxidation of acetic acid or acetyl equivalent provides energy for storage in phosphate bonds (as in ATP) called also citric acid cycle, tricarboxylic acid cycleKrebs Sir Hans Adolf (1900-1981)German-British biochemist. Krebs made major contributions to the understanding of metabolic processes. In 1932 he discovered with the German biochemist Kurt Henseleit a series of chemical reactions occurring in mammalian tissue by which ammonia is converted to urea. In 1937 he discovered an essential series of intermediate reactions in the oxidation of foodstuffs: the citric acid cycle. Now known as the Krebs cycle, these reactions have proved to be of vital importance in our understanding of metabolic processes in the cell. In 1953 he was awarded the Nobel Prize for Physiology or Medicine for his researches in metabolic processes.
* * *a complex cycle of enzyme-catalysed reactions, occurring within the cells of all living animals, in which acetate, in the presence of oxygen, is broken down to produce energy in the form of ATP (via the electron transport chain) and carbon dioxide. The cycle is the final step in the oxidation of carbohydrates, fats, and proteins; some of the intermediary products of the cycle are used in the synthesis of amino acids.Sir H. A. Krebbs (1900-81), British biochemist
* * *tricarboxylic acid c.
Medical dictionary. 2011.