in·te·grin 'in(t)-ə-grən n any of various glycoproteins that are found on cell surfaces (as of white blood cells or platelets), that are composed of two dissimilar polypeptide chains, that are receptors for various proteins which typically bind to the tripeptide ligand consisting of arginine, glycine, and aspartic acid, that promote adhesion of cells (as T cells) to other cells (as endothelial cells) or to extracellular material (as fibronectin or laminin), and that mediate various biological processes (as phagocytosis, wound healing, and embryogenesis)

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in·teg·rin (in-tegґrin) any of a family of heterodimeric cell adhesion molecules, consisting of two noncovalently linked polypeptide chains, designated α and β, that mediate cell-to-cell and cell-to–extracellular matrix interactions.

Medical dictionary. 2011.

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