Tolerance, immune

Tolerance, immune
A state of unresponsiveness to a specific antigen (immune stimulus) or group of antigens to which a person is normally responsive. Immune tolerance can result from a number of causes, including: {{}}Prior contact with the same antigen in fetal life or the newborn period when the immune system was not yet mature; Prior contact with the antigen in extremely high or low doses; Exposure to radiation, chemotherapy drugs, or other agents that impair the immune system; Genetic diseases of the immune system; Acquired diseases of the immune system such as HIV/AIDS.

Medical dictionary. 2011.

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