immunoconjugate

immunoconjugate
im·mu·no·con·ju·gate -'kän-ji-gət, -jə-.gāt n a complex of an antibody and a toxic agent (as a drug) used to kill or destroy a targeted antigen (as a cancer cell)

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im·mu·no·con·ju·gate (im″u-no-konґj-gāt) a conjugate comprising an immune substance such as an antibody and a diagnostic or therapeutic substance such as a cytotoxic compound or a radioisotope, used especially to target specific cells in cancer therapy.

Medical dictionary. 2011.

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  • Immunoconjugate — Immunoconjugates are antibodies conjugated to a second molecule, usually a toxin, radioisotope or label. [cite journal |author=Goldenberg DM, Sharkey RM |title=Novel radiolabeled antibody conjugates |journal=Oncogene |volume=26 |issue=25… …   Wikipedia

  • immunoconjugate — noun An antibody that has a second material as a conjugate …   Wiktionary

  • cBR96-doxorubicin immunoconjugate — A substance being studied in the treatment of cancer. It combines a monoclonal antibody with the anticancer drug doxorubicin. Monoclonal antibodies are substances that are made in the laboratory and that can locate and bind to cancer cells.… …   English dictionary of cancer terms

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  • PSCA (gene) — Prostate stem cell antigen, also known as PSCA, is a human gene.cite web | title = Entrez Gene: PSCA prostate stem cell antigen| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=8000| accessdate = ] PBB… …   Wikipedia

  • Drug Targeting — oder Targeted Drug Delivery ist die zielgerichtete und selektive Anreicherung oder Freisetzung eines Arzneistoffs am gewünschten Wirkort nach einer systemischen Verabreichung eines Medikaments. Auf diese Weise sollen die Effektivität der Wirkung… …   Deutsch Wikipedia

  • radioimmunoconjugate — noun An immunoconjugate that contains a radionuclide …   Wiktionary

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