Howell-Jolly body

Howell-Jolly body
How·ell-Jol·ly body 'hau̇-əl-zhȯ-'lē-, -'jäl-ē- n one of the basophilic granules that are prob. nuclear fragments, that sometimes occur in red blood cells, and that indicate by their appearance in circulating blood that red cells are leaving the bone marrow while incompletely mature (as in certain anemias)
Howell William Henry (1860-1945)
American physiologist. Howell was one of the leading physiologists of his time. His early contributions to physiology concerned the circulatory system, nerve tissue, and the components of blood. His later researches dealt with the coagulation of blood. He described what are now known as Howell-Jolly bodies in an article published in 1890.
Jol·ly zhȯ-lē Justin-Marie-Jules (1870-1953)
French histologist. Jolly did research on the morphology of blood and blood-forming tissues and on mammalian embryology. Independently of Howell, he described the Howell-Jolly bodies in a series of articles published 1905-1907.

Medical dictionary. 2011.

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  • Howell-Jolly body — Howell Jolly bodies are histopathological findings of basophilic nuclear remnants (clusters of DNA) in circulating erythrocytes. During maturation in the bone marrow erythrocytes normally expel their nuclei, but in some cases a small portion of… …   Wikipedia

  • howell-jolly body — zhȯˈlē , ˈjälē noun Usage: usually capitalized H&J Etymology: after William H. Howell died 1945 American physiologist and Justin M. J. Jolly died 1953 French physician : one of the basophilic granules that are probably nuclear fragments, that… …   Useful english dictionary

  • Howell-Jolly bodies — How·ell Jol·ly bodies (houґəl zho leґ) [W.H. Howell; Justin Marie Jules Jolly, French histologist, 1870–1953] see under body …   Medical dictionary

  • body — 1. The head, neck, trunk, and extremities. The human b., consisting of head (caput), neck (collum), trunk (truncus), and limbs (membra). 2. The material part of a human, as distinguished from the …   Medical dictionary

  • Jolly bodies — Jol·ly bodies (zho leґ) [Justin Marie Jules Jolly, French histologist, 1870–1953] Howell Jolly bodies; see under body …   Medical dictionary

  • Inclusion body — Inclusion bodies are nuclear or cytoplasmic aggregates of stainable substances, usually proteins. They typically represent sites of viral multiplication in a bacterium or a eukaryotic cell and usually consist of viral capsid proteins. Inclusion… …   Wikipedia

  • William Henry Howell — William Henry Howell, Ph.D., M.D., LL.D., Sc.D. (20 February 1860 ndash; 6 February 1945) was an American physiologist. He pioneered the use of heparin as a blood anti coagulant.William Henry Howell was born in Baltimore, Maryland and graduated… …   Wikipedia

  • Jolly — Friedrich, German neurologist, 1844–1904. See J. reaction. Justin, French histologist, 1870–1953. See J. bodies, under body, Howell J. bodies, under body …   Medical dictionary

  • Howell — William H., U.S. physiologist, 1860–1945. See H. unit, H. Jolly bodies, under body …   Medical dictionary

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