Freund's adjuvant

Freund's adjuvant
Freund's adjuvant 'frȯin(d)z-, 'frȯin(t)s- n any of several oil and water emulsions that contain antigens and are used to stimulate antibody production in experimental animals
Freund 'frȯind Jules Thomas (1890-1960)
American immunologist. Freund was a pioneer in immunological research who developed basic laboratory methods that are now standard. He is known above all for his work on adjuvants that enhance the effectiveness of vaccines. In a 1944 article he discussed such adjuvants as paraffin oil, lanolin-like substances, and killed tubercle bacilli. Other areas of his research were the mechanisms of allergy, antibody formation, toxin-antitoxin reaction, tuberculosis, poliomyelitis, and malaria.

Medical dictionary. 2011.

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  • Freund's adjuvant — is an antigen solution emulsified in mineral oil, used as an immunopotentiator (booster of the immune system). FormsThe so called complete form (CFA) is composed of inactivated and dried mycobacteria, usually Mycobacterium tuberculosis (the… …   Wikipedia

  • freund's adjuvant — ˈfrȯin(d)z noun Usage: usually capitalized F Etymology: after Jules T. Freund b1890 American immunologist : any of various substances (as lanolin, paraffin oil, or killed tubercle bacilli) added to an antigen to enhance its antigenicity * * *… …   Useful english dictionary

  • Freund's adjuvant — A water in oil emulsion used experimentally for stimulating a vigorous immune response to an antigen (that is in the aqueous phase). Complete Freund s adjuvant contains heat killed tubercle bacilli; these are omitted from Freund s incomplete… …   Dictionary of molecular biology

  • Freund's adjuvant — /froyndz/, Immunol. a water in oil emulsion injected with immunogen (Freund s incomplete adjuvant) or with immunogen and killed mycobacteria (Freund s complete adjuvant) to enhance the immune response to the immunogen. [1945 50; after Jules… …   Universalium

  • Freund — (German for friend ) is a surname and may refer to:* Ernst Freund * Gisèle Freund (1912 2000), photographer * Jules T. Freund * Karl Freund * Kurt Freund * Michael Freund * Steffen Freund, German soccer player * Tom Freund * Wilhelm Freund (1806… …   Wikipedia

  • Freund'sadjuvant — Freund s adjuvant (froindz) n. A substance consisting of killed microorganisms, such as mycobacteria, in an oil and water emulsion that is administered to induce and enhance the formation of antibodies.   [After Jules T. Freund (1890 1960),… …   Universalium

  • Adjuvant — An adjuvant (from Latin, adiuvare: to aid) is a pharmacological or immunological agent that modifies the effect of other agents, such as a drug or vaccine, while having few if any direct effects when given by itself. They are often included in… …   Wikipedia

  • adjuvant — Additional components added to a system to affect action of its main component, typically to increase immune response to an antigen. See Freund s adjuvant …   Dictionary of molecular biology

  • Freund adjuvant — Freund adjuvant. См. адъювант Фрейнда. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • incomplete Freund's adjuvant — A drug used in vaccine therapy to stimulate the immune system …   English dictionary of cancer terms

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