fil·gras·tim fil-'gras-təm n a genetically engineered human granulocyte colony-stimulating factor used to decrease the incidence of infection esp. as manifested by febrile neutropenia in patients affected with nonmyeloid malignant tumors see NEUPOGEN

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fil·gras·tim (fil-grasґtim) a human granulocyte colony-stimulating factor (G-CSF) produced by recombinant DNA technology, used to stimulate neutrophil production, reduce the duration of neutropenia, and reduce the incidence of infection in patients receiving myelosuppressive chemotherapy for nonmyeloid malignancies or following induction or consolidation chemotherapy for acute myelogenous leukemia, to accelerate recovery and promote engraftment after bone marrow transplantation, to enhance peripheral progenitor cell yield in autologous hematopoietic stem cell transplantation, and to treat chronic, severe neutropenia; administered subcutaneously or intravenously.

Medical dictionary. 2011.

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  • filgrastim — factor estimulante de colonias de granulocitos/monocitos idéntico (con la excepción de una metionina en el extremo amino terminal) al humano, producido por recombinación genética. Se utiliza para tratar la neutropenia crónica congénita o inducida …   Diccionario médico

  • Filgrastim — Not to be confused with granulocyte macrophage colony stimulating factor. Filgrastim Systematic (IUPAC) name Human granulocyte colony stimulating factor Clinical dat …   Wikipedia

  • filgrastim — A colony stimulating factor that stimulates the production of neutrophils (a type of white blood cell). It is a cytokine that is a type of hematopoietic (blood forming) agent. Also called granulocyte colony stimulating factor and G CSF …   English dictionary of cancer terms

  • filgrastim-SD/01 — A drug used to increase numbers of white blood cells in patients who are receiving chemotherapy. It is a type of colony stimulating factor. Also called pegfilgrastim and Neulasta …   English dictionary of cancer terms

  • filgrastim — …   Useful english dictionary

  • Granulocyte colony-stimulating factor — Not to be confused with granulocyte macrophage colony stimulating factor. Colony stimulating factor 3 (granulocyte) Crystal structure of 3 molecules of human G CSF. From PDB …   Wikipedia

  • G-CSF — Granulocyte colony stimulating factor Bändermodell des G CSF Trimer nach …   Deutsch Wikipedia

  • Hematopoietic stem cell transplantation — HSCT redirects here. For the supersonic aircraft, see High Speed Civil Transport. Hematopoietic stem cell transplantation Intervention ICD 9 CM 41.0 MeSH …   Wikipedia

  • Pegfilgrastim — Systematic (IUPAC) name N (3 Hydroxypropyl)Methionylcolony stimulating Factor (human), 1 Ether with .Alpha. Methyl .Omega. Hydroxypoly(Oxyethylene) Clinical data Trade names Neulasta AHFS/ …   Wikipedia

  • Intas Biopharmaceuticals — Infobox Company company name = Intas Biopharmaceuticals Ltd. company company type = Public Limited foundation = 2006 location = Ahmedabad, India key people = Dr. Urmish Chudgar,MD industry = Biotechnology products = Neukine: GCSF/Filgrastim,… …   Wikipedia

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