fetal hemoglobin

fetal hemoglobin
fetal hemoglobin n hemoglobin that consists of two alpha chains and two gamma chains and that predominates in the blood of a newborn and persists in increased proportions in some forms of anemia (as thalassemia) called also hemoglobin F

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the hemoglobin normally comprising more than half of that in the fetus, composed of two alpha and two gamma polypeptides (α2Aγ2F); it has higher affinity for oxygen under physiologic conditions than does hemoglobin A. It is present in minimal amounts in adulthood and is abnormally elevated in aplastic anemia, leukemia, and certain types of thalassemia. Called also h. F.

Medical dictionary. 2011.

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  • Fetal hemoglobin — Fetal hemoglobin, or Foetal haemoglobin in British English, (also hemoglobin F or HbF) is the main oxygen transport protein in the fetus during the last seven months of development in the uterus and in the newborn until roughly 6 months old.… …   Wikipedia

  • fetal hemoglobin — fetal hemoglobin. См. гемоглобин F. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • fetal hemoglobin — noun Date: 1950 a hemoglobin variant that predominates in the blood of a newborn and persists in increased proportions in some forms of anemia (as thalassemia) …   New Collegiate Dictionary

  • fetal hemoglobin — noun : a hemoglobin variant that predominates in the blood of a newborn and persists in increased proportions in some forms of anemia (as thalassemia) …   Useful english dictionary

  • Hereditary persistence of fetal hemoglobin — (HPFH, BrE: Hereditary persistence of foetal haemoglobin ) is a benign condition in which significant fetal hemoglobin (hemoglobin F) production continues well into adulthood, disregarding the normal shutoff point after which only adult type… …   Wikipedia

  • hereditary persistence of fetal hemoglobin — continued production of fetal hemoglobin beyond the point when it is normally replaced by hemoglobin A. Heterozygotes are asymptomatic, while homozygotes have hypochromic microcytic erythrocytes and may have a mild type of thalassemia …   Medical dictionary

  • hereditary fetal hemoglobin persistancy — hereditary fetal hemoglobin persistancy. См. наследственная персистенция фетального гемоглобина. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Hemoglobin — Hemoglobin, human, adult (heterotetramer, (αβ)2) Structure of human hemoglobin. The protein s α and β subunits are in red and blue, and the iron containing heme groups in green. Fro …   Wikipedia

  • Fetal protein — Fetal proteins are simply proteins present at highest levels at the fetus stage. Often related proteins assume similar roles after birth or in the embryo, in which case the fetal varieties are called fetal isoforms. Sometimes the genes coding… …   Wikipedia

  • hemoglobin F — n FETAL HEMOGLOBIN * * * fetal h …   Medical dictionary

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