familial adenomatous polyposis
- familial adenomatous polyposis
familial adenomatous polyposis n a disease of the large intestine that is marked by the formation esp. in the colon and rectum of numerous adenomatous polyps which typically become malignant if left untreated, that may be either asymptomatic or accompanied by diarrhea or bleeding, and that is inherited as an autosomal dominant trait
abbr. FAP called also familial polyposis
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(FAP), familial polyposis coli, familial intestinal polyposis an autosomal dominant syndrome in which multiple adenomatous polyps line the mucous membrane of the intestine, particularly the colon, with onset at about puberty; caused by mutation in the APC gene (locus: 5q21-q22), a tumor suppressor gene. It is characterized by weight loss, bowel obstruction, and bloody diarrhea; extracolonic signs include pigmented retinal lesions, jaw cysts, sebaceous cysts, and osteomas. If untreated it progresses to malignancy. There is variant form of later onset; see attenuated familial adenomatous p.
Medical dictionary.
2011.
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Familial adenomatous polyposis — Classification and external resources Endoscopic image of sigmoid colon of patient with familial adenomatous polyposis. ICD 10 C … Wikipedia
Familial adenomatous polyposis (FAP) — A syndrome characterized by the formation of thousands of polyps in the colon and rectum with colorectal cancer the inevitable consequence. Polyps can also occur in the stomach, duodenum and the terminal ileum. The polyps most often begin to form … Medical dictionary
familial adenomatous polyposis — noun Etymology: polyposis presence of polyps, from New Latin, from polypus polyp + osis Date: 1976 an inherited disease of the large intestine marked by the formation especially in the colon and rectum of numerous glandular polyps which typically … New Collegiate Dictionary
familial adenomatous polyposis — FAP. An inherited condition in which numerous polyps (growths that protrude from mucous membranes) form on the inside walls of the colon and rectum. It increases the risk for colorectal cancer. Also called FAP and familial polyposis … English dictionary of cancer terms
familial adenomatous polyposis — noun : a disease of the large intestine that is marked by the formation especially in the colon and rectum of numerous glandular polyps of epithelial origin which typically become malignant if left untreated, that may be either asymptomatic or… … Useful english dictionary
familial adenomatous polyposis — see polyposis … Medical dictionary
familial adenomatous polyposis — FAP; see polyposis … The new mediacal dictionary
Adenomatous-polyposis-coli-Protein — Masse/Länge Primärstruktur 2843 aa; 311,6 kD … Deutsch Wikipedia
Polyposis registries — exist for the purpose of understanding the genetic disease familial adenomatous polyposis. The registries provide a service to doctors for identification, surveillance and management of families and individuals with high colorectal cancer risk… … Wikipedia
polyposis coli — (= adenomatous polyposis coli; Familial adenomatous polyposis; FAP) Hereditary disorder (Mendelian dominant) characterized by the development of hundreds of adenomatous polyps in the large intestine, which show a tendency to progress to… … Dictionary of molecular biology
