cutaneous T-cell lymphoma

cutaneous T-cell lymphoma
cutaneous T-cell lymphoma n any of several lymphomas (as mycosis fungoides or Sezary syndrome) that are marked by clusters of malignant helper T cells in the epidermis causing skin lesions and eruptions which typically progress to tumors and may spread to lymph nodes and internal organs

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a group of lymphomas including a spectrum of disorders, all of which exhibit both clonal expansion of malignant T lymphocytes and malignant infiltration of the skin. The lymphocytes have been arrested at varying stages of differentiation into helper cells, and skin infiltration is often the chief or only manifestation of disease. Mycosis fungoides and Sйzary syndrome are the best characterized of these disorders.

Medical dictionary. 2011.

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