Churg-Strauss syndrome

Churg-Strauss syndrome 'chərg-'strau̇s- n granulomatosis that typically affects the lungs but may involve other organs or tissues (as the skin or kidneys), is accompanied by vasculitis, eosinophilia, and asthma, and is sometimes considered to be a variant form of polyarteritis nodosa

Churg Jacob (b 1910), and

Strauss Lotte (1913-1985)

American pathologists. Churg and Strauss spent virtually the whole of their medical careers at Mount Sinai Hospital and Medical School in New York City. Churg's areas of research included vascular diseases, renal structure and diseases, and pneumoconioses. Strauss specialized in pediatric pathology. They described the syndrome that bears their names in articles published in 1951.

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a clinical syndrome comprising severe asthma associated with an increased eosinophil count in the peripheral blood and eosinophilic deposits in the small vessels of the lungs. It usually responds to oral corticosteroids. Untreated, it may result in severe and widespread systemic angiitis.

J. Churg (1910- ) and L. Strauss (1913- ), US pathologists

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a type of small vessel vasculitis that is also grouped with the systemic necrotizing vasculitides and has prominent lung involvement with severe asthma, eosinophilia, and granulomatous reactions. If present, cutaneous lesions consist of tender subcutaneous nodules, large ecchymotic plaques, and cutaneous infarcts. There are several different types; one is a type of ANCA-associated vasculitis. Called also allergic granulomatosis, allergic granulomatous angiitis, and Churg-Strauss vasculitis.