chloride shift

chloride shift
chloride shift -'shift n the passage of chloride ions from the blood plasma into the red blood cells when carbon dioxide enters the plasma from the tissues and their return to the plasma when the carbon dioxide is discharged in the lungs that is a major factor both in maintenance of blood pH and in transport of carbon dioxide

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the exchange of chloride (Cl) and bicarbonate (HCO3) between the plasma and the red blood cells; it takes place whenever HCO3 is generated or decomposed within the red cells.

Medical dictionary. 2011.

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