central pontine myelinolysis

central pontine myelinolysis
central pontine myelinolysis n disintegration of the myelin sheaths in the pons that is associated with malnutrition and esp. with alcoholism

* * *

symmetric demyelination affecting the base and tegmentum of the pons, possibly caused by rapid correction of hyponatremia, and characterized by rapidly progressing paraparesis or quadriparesis, dysarthria, dysphagia, and impaired consciousness; areas of demyelination may also occur outside the pons. It is associated with a variety of conditions, including alcoholism, malignancies, burns, and liver transplantation.

Medical dictionary. 2011.

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