biguanide

biguanide
bi·gua·nide (')bī-'gwän-.īd, -əd n any of a group of hypoglycemia-inducing drugs (as metformin) used esp. in the treatment of diabetes see PROGUANIL

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n.
one of the group of drugs including metformin, which is used to treat noninsulin-dependent (type 2) diabetes mellitus. Biguanides are oral hypoglycaemic drug: they act by reducing the release of glucose from the liver and increasing glucose uptake by muscles.

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bi·gua·nide (bi-gwahґnīd) 1. a base: 2. any of a group of substituted derivatives of biguanide, which are used as oral antihyperglycemic agents; they increase insulin action in peripheral tissues and by inhibiting gluconeogenesis decrease hepatic glucose production.


Medical dictionary. 2011.

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  • Biguanide — IUPAC na …   Wikipedia

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  • Biguanide —   Plural, von Guanylguanidin abgeleitete synthetische Verbindungen. Einige davon haben blutzuckersenkende Wirkung und wurden deshalb als orale Antidiabetika angewendet; aufgrund gefährlicher Nebenwirkungen wurden sie 1978 mit Ausnahme von… …   Universal-Lexikon

  • Biguanide — Biguanid Derivate sind eine alte Gruppe von Arzneistoffen, die zur Behandlung von Diabetes mellitus Verwendung finden. Ihre Bedeutung als sogenannte orale Antidiabetika hat seit der Entwicklung neuerer Wirkstoffe stark abgenommen. Einzig… …   Deutsch Wikipedia

  • biguanide — biguanidas statusas T sritis chemija formulė [H₂NC(=NH)]₂NH atitikmenys: angl. biguanide rus. бигуанид …   Chemijos terminų aiškinamasis žodynas

  • biguanide — noun a) The molecule CHN. b) Any of a class of antihyperglycemic and antimalarial drugs based upon this molecule. Syn: diguanide, carbamimidoylguanidine …   Wiktionary

  • biguanide — bi·gua·nide …   English syllables

  • biguanide — n. one of the group of drugs including metformin, which is used to treat noninsulin dependent (type 2) diabetes mellitus. Biguanides are oral hypoglycaemic drugs: they act by reducing the release of glucose from the liver and increasing glucose… …   The new mediacal dictionary

  • biguanide — (ˈ)bī|gwäˌnīd, nə̇d noun ( s) Etymology: International Scientific Vocabulary bi (I) + guan (from guanidine) + ide : a strong amorphous base NH[C( = NH)NH2]2 some of whose derivatives (as aryl …   Useful english dictionary

  • Бигуанид (Biguanide) — представитель группы лекарственных веществ, включающей метформин; применяется для лечения инсулинонсзависимого сахарного диабета (II типа). Бигуаниды являются оральными гипогликемическими лекарственными веществами; их действие связано с… …   Медицинские термины

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