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au·to·re·ac·tive (aw″to-re-akґtiv) reacting with autoantigens; said of B and T lymphocytes.Medical dictionary. 2011.
autoreactive — adjective Acting against the organism by which it was produced an autoreactive T cell clone See Also: autoimmune … Wiktionary
Systemic lupus erythematosus — For other uses, see lupus (disambiguation). Systemic lupus erythematosus Classification and external resources The typical butterfly rash found in lupus ICD 10 L … Wikipedia
Denise Faustman — Denise L. Faustman, (born 1958[1]) is a U.S. physician and medical researcher. An Associate Professor of Medicine at Harvard University and Director of the Immunobiology Laboratory at Massachusetts General Hospital, her work specializes in… … Wikipedia
Tovaxin — is a novel anti T cell therapeutic vaccine that parallels the concept of autologous cancer vaccines. Instead of modifying cancerous cells, TovaxinTM consists of attenuated autoreactive T cells. Tovaxin is being developed by Opexa Therapeutics in… … Wikipedia
Molecular mimicry — is defined as the theoretical possibility that sequence similarities between foreign and self peptides are sufficient to result in the cross activation of autoreactive T or B cells by pathogen derived peptides. Despite the promiscuity of several… … Wikipedia
Thymus — Infobox Anatomy Name = PAGENAME Latin = GraySubject = 274 GrayPage = 1273 Caption = Thymus Caption2 = The thymus of a full term fetus, exposed in situ. Precursor = third branchial pouch System = Artery = derived from internal mammary artery,… … Wikipedia
Cross-presentation — The term cross presentation denotes the ability of certain antigen presenting cells to take up, process and present extracellular antigens with MHC class I molecules to CD8 T cells (cytotoxic T cells). Cross priming describes the stimulation of… … Wikipedia
T cell vaccination — is immunization with inactivated autoreactive T cells. The concept of T cell vaccination is, at least partially, analogous to classical vaccination against infectious disease. However, the agents to be eliminated or neutralized are not foreign… … Wikipedia
Thymocyte — Thymocytes are T cell precursors which develop in the thymus. The processes of beta selection, positive selection and negative selection shape the population thymocytes into a peripheral pool of T cells that are able to respond to foreign… … Wikipedia
Therapies under investigation for multiple sclerosis — Scientists continue their efforts to create new and better therapies for multiple sclerosis. There are a number of treatments under investigation that may improve function, curtail attacks, or limit the progression of the underlying disease. Many … Wikipedia
