Sex region Y, a region on the Y chromosome that determines the sex of the individual. SRY is necessary and sufficient for male sex determination. It is the testis-determining factor. Mutations in SRY give rise to XY females with gonadal dysgenesis who appear to be normal females at birth, but at puberty do not develop secondary sexual characteristics (breasts, etc.), do not menstruate, and have streak (fibrous) gonads without eggs. There is a high incidence of neoplasia (gonadoblastoma and germinoma) in the streak gonads. Translocation (transfer) of the part of the Y chromosome containing SRY to the X chromosome results in XX males — individuals who have XX sex chromosomes but appear male. SRY resides in chromosome band Yp11.3 and encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA binding proteins.
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sex-determining region on Y chromosome

Medical dictionary. 2011.

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  • SRY — ist die Abkürzung für: Sex determining region of Y (englisch), auf Deutsch in etwa: die das Geschlecht bestimmenden Region auf dem Y Chromosom den Internationalen Flughafencode von Sary im Iran umgangssprachliche Abkürzung für das Englische Wort… …   Deutsch Wikipedia

  • SRY — Símbolo del gen de la masculinidad situado en la región que determina el sexo en el cromosoma Y. Se piensa que actúa como un sistema de control principal, con capacidad para desactivar o activar otros genes implicados en el desarrollo …   Diccionario médico

  • SRY — abbreviation sorry: used in e mails and TEXT MESSAGES …   Usage of the words and phrases in modern English

  • śry — Definition: West Semitic, to strive, strive for, save, protect. Israel, from Hebrew yiśrāɔēl, God has striven, God has saved, from yiśrā, he has striven, saved, archaic preterite of śārâ, to strive, persevere …   The American Heritage dictionary of the English language

  • šry — Definition: To loosen, remove, begin. Tishri, from Hebrew tišrî, a month name, from Akkadian tašrītu, beginning, name of a month corresponding to parts of September and October, from šurrû, to begin, derived stem of *šarû, to begin …   The American Heritage dictionary of the English language

  • SRY — abbreviation sorry: used in emails and text messages Thesaurus: abbreviations used in emails and text messageshyponym ways of saying you are sorry or regret somethingsynonym communicating by email or text messagehyponym …   Useful english dictionary

  • SRY — Image of the protein SRY bound to DNA. Este artículo o …   Wikipedia Español

  • SRY — Ген SRY (англ. Sex determining Region Y) располагается на Y хромосоме большинства млекопитающих, и принимает участие в развитии организма по мужскому типу. Ген SRY не имеет интронов и кодирует белковый фактор развития семенников, также… …   Википедия

  • SRY — Le gène SRY (Sex determining Region of Y chromosome) est un gène architecte situé sur le bras P (court) du chromosome Y en position Yp11.31. La transcription et la traduction du gène SRY aboutissent à la synthèse de la protéine TDF (Testis… …   Wikipédia en Français

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