Excess protein in the urine. Some protein is normal in the urine. Too much means protein is leaking through the kidney, most often through the glomeruli. The main protein in human blood and the key to the regulation of the osmotic pressure of blood is albumin. Proteinuria is synonymous with albuminuria.
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1. Presence of urinary protein in amounts greater than 0.3 g in a 24-hour urine collection or in concentrations greater than 1 g/L (1+ to 2+ by standard turbidometric methods) in a random urine collection on two or more occasions at least 6 hours apart; specimens must be clean, voided midstream, or obtained by catheterization. 2. SYN: albuminuria. [protein + G. ouron, urine]
- Bence Jones p. presence of Bence Jones proteins in the urine, usually indicative of a neoplastic process such as multiple myeloma, amyloidosis, or Waldenström macroglobulinemia.
- gestational p. the presence of p. during or under the influence of pregnancy in the absence of hypertension, edema, renal infection, or known intrinsic renovascular disease.
- isolated p. p. in a patient who is asymptomatic, has normal renal function and urinary sediment, and has no manifestation of systemic disease upon initial examination.
- nonisolated p. p. associated with other abnormalities.
- orthostatic p., postural p. SYN: orthostatic albuminuria.

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pro·tein·uria .prōt-ən-'(y)u̇r-ē-ə, .prō-.tēn-, .prōt-ē-ən- n the presence of excess protein in the urine
pro·tein·uric -'(y)u̇r-ik adj

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the presence of protein in the urine. This may indicate the presence of damage to, or disease of, the kidneys. See also albuminuria.

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pro·tein·uria (pro″te-nuґre-ə) excessive serum proteins in the urine, such as in renal disease, after strenuous exercise, and with dehydration. Called also albuminuria. proteinuric adj

Medical dictionary. 2011.

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