The family member through whom a family’s medical history comes to light. For example, a proband might be a baby with Down syndrome. The proband may also be called the index case, propositus (if male), or proposita (if female).
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In human genetics, the patient or member of the family that brings a family under study. SYN: index case. [L. probo, to test, prove]

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pro·band 'prō n an individual being studied (as in a genetic investigation): SUBJECT (1) <the \proband had four negative sibs> called also propositus

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pro·band (proґband) [Ger., from L. probandus “the one to be tested”] an affected person ascertained independently of relatives in a genetic study. Called also propositus.

Medical dictionary. 2011.

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Look at other dictionaries:

  • Proband — is a term used most often in medical genetics and other medical fields to denote a particular subject (person or animal) being studied or reported on. On pedigrees, the proband is noted with an arrow and the box (male) or circle (female) shaded… …   Wikipedia

  • proband — probánd s. m., adj. m., pl. probánzi; f. sg. probándă, pl. probánde Trimis de siveco, 01.08.2005. Sursa: Dicţionar ortografic  PROBÁND, Ă s.m. şi f …   Dicționar Român

  • proband — proband. См. пробанд. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • pròband — m 〈G mn nādā〉 knjiš. 1. {{001f}}onaj koji je na pokusnom i sl. radu; stažist, kandidat 2. {{001f}}kat. novak, iskušenik …   Veliki rječnik hrvatskoga jezika

  • Proband — Proband,der:⇨Versuchsperson …   Das Wörterbuch der Synonyme

  • proband — 1929, from L. probandus, gerundive of probare (see PROVE (Cf. prove)) …   Etymology dictionary

  • proband — pròband m <G mn nādā> DEFINICIJA knjiš. 1. onaj koji je na pokusnom i sl. radu; stažist, kandidat 2. kat. novak, iskušenik ETIMOLOGIJA vidi probacija …   Hrvatski jezični portal

  • proband — [prō′band΄] n. [< L probandus, ger. of probare, to test: see PROBE] PROPOSITUS …   English World dictionary

  • Proband — Ein Proband (lat. probare, „prüfen“) ist eine Person, die sich einer Prüfung unterzieht oder als Test oder Vergleichsperson einer Prüfung im weitesten Sinne unterzogen wird. Wörtlicher und übertragener Sinn Im wörtlichen Sinn ist ein Proband ein… …   Deutsch Wikipedia

  • Proband — En génétique, le proband (du latin probare tester) désigne la personne atteinte de la maladie génétique à partir de laquelle on fait le conseil génétique. Portail de la médecine Catégorie  …   Wikipédia en Français

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