IC50

IC50
inhibitory concentration of 50%

Medical dictionary. 2011.

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  • IC50 — IC50, или концентрация полумаксимального ингибирования  показатель эффективности лиганда при ингибирующем биохимическим или биологическим взаимодействии. IC50 является количественным индикатором, который показывает, сколько нужно лиганда… …   Википедия

  • IC50 — The IC50 is a measure of the effectiveness of a compound in inhibiting biological or biochemical function. Often, the compound in question is a drug candidate. This quantitative measure indicates how much of a particular drug or other substance… …   Wikipedia

  • Ic50 — Als mittlere inhibitorische Konzentration (IC50) wird die Konzentration eines Inhibitors bezeichnet, bei der eine halbmaximale Inhibition beobachtet wird. In der Pharmakologie wird die IC50 verwendet, um die Wirkstärke eines Antagonisten… …   Deutsch Wikipedia

  • IC50 — Als mittlere inhibitorische Konzentration (IC50) wird die Konzentration eines Inhibitors bezeichnet, bei der eine halbmaximale Inhibition beobachtet wird. In der Pharmakologie wird die IC50 verwendet, um die Wirkstärke eines Antagonisten… …   Deutsch Wikipedia

  • IC50 — Concentration of an inhibitor at which 50% inhibition of the response is seen; should only be used of in vitrotest systems. Needs to be used with caution because ED50 (for example) is the concentration that causes an effect in 50% of tests not… …   Dictionary of molecular biology

  • IC50 — • inhibitory concentration of 50% …   Dictionary of medical acronyms & abbreviations

  • Half maximal effective concentration — The term half maximal effective concentration (EC50) refers to the concentration of a drug or antibody which induces a response halfway between the baseline and maximum. [ [http://www.graphpad.com/curvefit/introduction89.htm Introducing… …   Wikipedia

  • Phosphodiesterase 2 — The PDE2 (phosphodiesterase 2) enzyme is one of 21 different phosphodiesterases (PDE) found in mammals. These different PDEs can be subdivided to 11 families (PDE1 – PDE11). The different PDEs of the same family are functionally related despite… …   Wikipedia

  • EC50 — For the UK postcode EC50, see EC postcode area. The term half maximal effective concentration (EC50) refers to the concentration of a drug, antibody or toxicant which induces a response halfway between the baseline and maximum after some… …   Wikipedia

  • PDE2 — The PDE2 (phosphodiesterase 2) enzyme is one of 21 different phosphodiesterases (PDE) found in mammals. These different PDEs can be subdivided to 11 families (PDE1 – PDE11). The different PDEs of the same family are functionally related despite… …   Wikipedia

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