- CTLA
- cytotoxic T lymphocyte antigen
Medical dictionary. 2011.
CTLA
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CTLA-4 — Cytotoxic T lymphocyte associated protein 4 Structure of murine CTLA4 (CD152) … Wikipedia
CTLA-4 — (= CD152) Type I transmembrane protein (20 kD) of the immunoglobulin superfamily. Found on activated T cells and binds to CD80 on B cells. Resembles CD28 but acts as a negative regulator of T cell activation. Cytoplasmic domain interacts with SH2 … Dictionary of molecular biology
CTLA — • cytotoxic T lymphocyte antigen … Dictionary of medical acronyms & abbreviations
Abatacept — Clinical data Trade names Orencia AHFS/Drugs.com monograph MedlinePlus … Wikipedia
B7 (protein) — B7 is a type of peripheral membrane protein found on activated antigen presenting cells (APC) that, when paired with either a CD28 or CD152 (CTLA 4) surface protein on a T cell, can produce a costimulatory signal to enhance or decrease the… … Wikipedia
Ipilimumab — drugbox mab source = Human target = CTLA 4 CAS number = 477202 00 9 ATC prefix = ATC suffix = PubChem = DrugBank = C=6742 | H= 9972 | N=1732 | O=2004 | S=40 molecular weight = bioavailability = protein bound = metabolism = elimination half life … Wikipedia
CD278 — Inducible T cell co stimulator, also known as ICOS, is a human gene.cite web | title = Entrez Gene: ICOS inducible T cell co stimulator| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=29851| accessdate = ]… … Wikipedia
Belatacept — Clinical data AHFS/Drugs.com Consumer Drug Information MedlinePlus … Wikipedia
CD80 — PBB|geneid=941The protein CD80 (Cluster of Differentiation 80) is a molecule found on activated B cells and monocytes which provides a costimulatory signal necessary for T cell activation and survival. It is also known as B7.1. Its principal mode … Wikipedia
PD-1 — Programmed Death 1, or PD 1, is a Type I membrane protein of 268 amino acids. PD 1 is a member of the extended CD28/CTLA 4 family of T cell regulators.[1] The protein s structure includes an extracellular IgV domain followed by a transmembrane… … Wikipedia
