cytotoxic T lymphocyte antigen

Medical dictionary. 2011.

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  • CTLA-4 — Cytotoxic T lymphocyte associated protein 4 Structure of murine CTLA4 (CD152) …   Wikipedia

  • CTLA-4 — (= CD152) Type I transmembrane protein (20 kD) of the immunoglobulin superfamily. Found on activated T cells and binds to CD80 on B cells. Resembles CD28 but acts as a negative regulator of T cell activation. Cytoplasmic domain interacts with SH2 …   Dictionary of molecular biology

  • CTLA — • cytotoxic T lymphocyte antigen …   Dictionary of medical acronyms & abbreviations

  • Abatacept — Clinical data Trade names Orencia AHFS/Drugs.com monograph MedlinePlus …   Wikipedia

  • B7 (protein) — B7 is a type of peripheral membrane protein found on activated antigen presenting cells (APC) that, when paired with either a CD28 or CD152 (CTLA 4) surface protein on a T cell, can produce a costimulatory signal to enhance or decrease the… …   Wikipedia

  • Ipilimumab — drugbox mab source = Human target = CTLA 4 CAS number = 477202 00 9 ATC prefix = ATC suffix = PubChem = DrugBank = C=6742 | H= 9972 | N=1732 | O=2004 | S=40 molecular weight = bioavailability = protein bound = metabolism = elimination half life …   Wikipedia

  • CD278 — Inducible T cell co stimulator, also known as ICOS, is a human gene.cite web | title = Entrez Gene: ICOS inducible T cell co stimulator| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=29851| accessdate = ]… …   Wikipedia

  • Belatacept — Clinical data AHFS/Drugs.com Consumer Drug Information MedlinePlus …   Wikipedia

  • CD80 — PBB|geneid=941The protein CD80 (Cluster of Differentiation 80) is a molecule found on activated B cells and monocytes which provides a costimulatory signal necessary for T cell activation and survival. It is also known as B7.1. Its principal mode …   Wikipedia

  • PD-1 — Programmed Death 1, or PD 1, is a Type I membrane protein of 268 amino acids. PD 1 is a member of the extended CD28/CTLA 4 family of T cell regulators.[1] The protein s structure includes an extracellular IgV domain followed by a transmembrane… …   Wikipedia

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