Mycobacterium avium complex (MAC)
- Mycobacterium avium complex (MAC)
- MAC is a serious opportunistic infection caused by two similar bacteria (Mycobacterium avium and Mycobacterium intercellulare) found in the soil and dust particles. In AIDS, MAC can spread through the bloodstream to infect lymph nodes, bone marrow, liver, spleen, spinal fluid, lungs and intestinal tract. Typical symptoms of MAC include night sweats, weight loss, fever, fatigue, diarrhea and enlarged spleen. MAC is usually found in people with CD4 counts below 100. Clarithromycin, azithromycin, ethambutol, rifampin, clofazimine and rifabutin are some of the antibiotics commonly used in MAC prevention and treatment. (Based upon material prepared by Treatment Issues, a publication of Gay Men's Health Crisis, New York, NY.)
Medical dictionary.
2011.
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