- xenodiagnosis
- 1. A method of diagnosing acute or early Trypanosoma cruzi infection (Chagas disease) in humans. Infection-free (laboratory-reared) triatomine bugs are fed on the tissue of the suspected person and the trypanosome is identified by microscopic examination of the intestinal contents of the bug after a suitable incubation period. 2. A similar method of biologic diagnosis based upon experimental exposure of a parasite-free normal host capable of allowing the organism in question to multiply, enabling it to be more easily and reliably detected.
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xe·no·di·ag·no·sis .zen-ō-.dī-ig-'nō-səs, .zēn- n, pl -no·ses -.sēz the detection of a parasite (as of humans) by feeding supposedly infected material (as blood) to a suitable intermediate host (as an insect) and later examining the intermediate host for the parasitexe·no·di·ag·nos·tic -'näs-tik adj* * *
n.a procedure for diagnosing infections transmitted by insect carriers. Uninfected insects of the species known to carry the disease in question are allowed to suck the blood of a patient suspected of having the disease. A positive diagnosis is made if the disease parasites appear in the insects. This method has proved invaluable for diagnosing Chagas' disease, using reduviid bugs (the carriers), since the parasites are not always easily detected in blood smears.* * *
xeno·di·ag·no·sis (zen″o-di″əg-noґsis) [xeno- + diagnosis] a method of animal inoculation using laboratory-bred reduviids and larger animals for diagnosis of parasitic infections when it is not possible to demonstrate the infecting organism in blood films. Originally used for diagnosis of Trypanosoma cruzi infection (Chagas disease), the method is also used in Trichinella spiralis infections. In the original method, bugs are fed or offered the patient's blood through a membrane, and their feces or intestinal contents are examined later for trypanosomes. For the diagnosis of trichinosis, a muscle tissue sample from the patient is fed to laboratory rats to detect larvae of the parasite. xenodiagnostic adj
Medical dictionary. 2011.