urokinase

urokinase
SYN: plasminogen activator.

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uro·ki·nase .yu̇r-ō-'kī-.nās, -.nāz n an enzyme that is produced by the kidney and is found in human urine, that activates plasminogen, and that is used therapeutically to dissolve blood clots (as in the heart)

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n.
an enzyme produced in the kidney and also present in blood and urine that is capable of breaking up blood clots. It activates plasminogen directly to plasmin, which dissolves blood clots. See plasminogen activators.

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uro·ki·nase (UK) (u″ro-kiґnās) u-plasminogen activator; the term is used particularly to denote a pharmaceutical preparation of the enzyme, administered intravenously as a thrombolytic agent in the treatment of acute coronary arterial thrombosis and acute pulmonary embolism; also used to restore patency to intravenous catheters.

Medical dictionary. 2011.

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Look at other dictionaries:

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  • urokinase — ● urokinase nom féminin Enzyme produite par le rein et excrétée dans l urine …   Encyclopédie Universelle

  • urokinase — ☆ urokinase [yoor΄ō kī′nās΄, yoor΄ōkin′ās΄ ] n. [ URO 1 + KINASE] an enzyme found as a trace in human urine, used for dissolving blood clots …   English World dictionary

  • Urokinase — drugbox IUPAC name = Human urokinase Caption = The protease domain from urokinase in complex with and inhibitor CAS number = 9039 53 6 ATC prefix = B01 ATC suffix = AD04 ATC supplemental = PubChem = DrugBank = BTD00030 C=1376 | H=2145 | N=383 | O …   Wikipedia

  • Urokinase — U|ro|ki|na|se [↑ ur (1) u. ↑ Kinase] aus Harn oder Nierenzellkulturen gewinnbare, auch gentechnologisch herstellbare Serin Proteinase, die in zwei aktiven Formen (MG 54 000 bzw. 31 000) vorliegt. U. löst im Blutgerinnungssystem die… …   Universal-Lexikon

  • Urokinase receptor — The Urokinase receptor, also known as uPA receptor or uPAR or CD87 (Cluster of Differentiation 87), is multidomain glycoprotein tethered to the cell membrane with a glycosylphosphotidylinositol (GPI) anchor. uPAR was originally identified as a… …   Wikipedia

  • urokinase — noun Date: 1952 an enzyme that is produced by the kidney and found in urine, that activates plasminogen, and that is used therapeutically to dissolve blood clots (as in the heart) …   New Collegiate Dictionary

  • urokinase — Serine protease from kidney that is a plasminogen activator. Contains EGF like domain …   Dictionary of molecular biology

  • urokinase — /yoor euh kuy nays, nayz/, n. Biochem., Pharm. an enzyme, present in the blood and urine of mammals, that activates plasminogen and is used medicinally to dissolve blood clots. [1955 60; URO 1 + KINASE] * * * …   Universalium

  • urokinase — noun An enzyme, found in the urine, which converts plasminogen to plasmin, and is used in the treatment of deep vein thrombosis …   Wiktionary

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