A small (76 amino acyl residues) protein found in all cells of higher organisms and one whose structure has changed minimally during evolutionary history; involved in at least two processes; histone modification and intracellular protein breakdown.

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ubiq·ui·tin yü-'bik-wət-ən n a chiefly eukaryotic protein that when covalently bound to other cellular proteins marks them for proteolytic degradation

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ubiq·ui·tin (u-bikґwĭ-tin) a 76–amino acid polypeptide that is present in the cells of all higher animals and plants; it attaches to proteins during intracellular proteolysis, marking them for degradation by proteasomes.

Medical dictionary. 2011.

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  • Ubiquitin — is a highly conserved regulatory protein that is expressed in eukaryotes. Ubiquitination (or ubiquitylation) refers to the post translational modification of a protein by the covalent attachment (via an isopeptide bond) of one or more ubiquitin… …   Wikipedia

  • Ubiquitin — Bändermodell …   Deutsch Wikipedia

  • Ubiquitin B — Ubiquitin B, also known as UBB, is a human gene. PBB Summary section title = summary text = This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP dependent, nonlysosomal intracellular protein… …   Wikipedia

  • Ubiquitin C — Ubiquitin C, also known as UBC, is a human gene.cite web | title = Entrez Gene: UBC ubiquitin C| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=7316| accessdate = ] PBB Summary section title = summary text …   Wikipedia

  • ubiquitin — ubiquitin. См. убикитин. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • ubiquitin — A protein (8.5 kD) found in all eukaryotic cells. Can be linked to the lysine side chains of proteins by formation of an amide bond to its C terminal glycine in an ATP requiring process. The protein/ubiquitin complex is subject to rapid… …   Dictionary of molecular biology

  • Ubiquitin carboxy-terminal hydrolase L1 — (UCH L1) (EC number| is a deubiqutinating enzyme. PBB Summary section title = summary text = UCHL1 is a member of a gene family whose products hydrolyze small C terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression… …   Wikipedia

  • Ubiquitin-activating enzyme — Ubiquitin activating enzymes, also known as E1 enzymes, catalyze the first step in the ubiquitination reaction that targets a protein for degradation via the proteasome. The ubiquitination process covalently attaches ubiquitin, a short protein of …   Wikipedia

  • Ubiquitin-conjugating enzyme — Ubiquitin conjugating enzymes, also known as E2 enzymes and more rarely as ubiquitin carrier enzymes , perform the second step in the ubiquitination reaction that targets a protein for degradation via the proteasome.The ubiquitination process… …   Wikipedia

  • Ubiquitin-Protein-Ligase Parkin — Masse/Länge Primärstruktur 465 Aminosäuren …   Deutsch Wikipedia

  • Ubiquitin ligase — A ubiquitin ligase (also called an E3 ubiquitin ligase) is a protein that covalently attaches ubiquitin to a lysine on a target protein via an isopeptide bond. In general, the ubiquitin ligase is involved in polyubiquitination: A second ubiquitin …   Wikipedia

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