tubocurarine chloride

tubocurarine chloride
An alkaloid (obtained from the stems of Chondodendron, particularly C. tomentosum) that blocks the action of acetylcholine at the myoneural junction by occupying the receptors competitively; also blocks ganglionic transmission and releases histamine; used to produce muscular relaxation during surgical operations.

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[USP] a nondepolarizing neuromuscular blocking agent used for relaxation of skeletal muscles in surgery and convulsive therapy and in the diagnosis of myasthenia gravis. Administered intravenously or intramuscularly.

Medical dictionary. 2011.

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  • curare — /kyoo rahr ee, koo /, n. 1. a blackish, resinlike substance derived from tropical plants of the genus Strychnos, esp. S. toxifera, and from the root of pareira, used by certain South American Indians for poisoning arrows and employed in… …   Universalium

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