troponin

troponin
A globular protein of muscle that binds to tropomyosin and has considerable affinity for calcium ions; a central regulatory protein of muscle contraction. T. T binds to tropomyosin; t. I inhibits F-actin-myosin interactions; t. C is a calcium-binding protein and has a key role in muscle contraction.

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tro·po·nin 'trōp-ə-nən, 'träp-, -.nin n a protein of muscle that together with tropomyosin forms a regulatory protein complex controlling the interaction of actin and myosin and that when combined with calcium ions permits muscular contraction

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tro·po·nin (troґpo-nin) a complex of globular muscle proteins of the I band that inhibits contraction by blocking the interaction of actin and myosin; when combined with Ca2+, it so modifies the position of the tropomyosin molecules that contraction takes place. See Plate 32.

Medical dictionary. 2011.

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  • Troponin — is a complex of three regulatory proteins that is integral to muscle contraction in skeletal and cardiac muscle, but not smooth muscle. Troponin is attached to the protein tropomyosin and lies within the groove between actin filaments in muscle… …   Wikipedia

  • Troponin T — is a part of the troponin complex. It binds to tropomyosin, interlocking them to form a troponin tropomyosin complex.The tissue specific subtypes are: * Slow skeletal troponin T1, TNNT1 (19q13.4, OMIM2|191041) * Cardiac troponin T2, TNNT2 (1q32,… …   Wikipedia

  • Troponin I — is a part of the troponin complex. It binds to actin in thin myofilaments to hold the troponin tropomyosin complex in place. The letter I is given due to its inhibitory character.The tissue specific subtypes are: * Slow twitch skeletal muscle… …   Wikipedia

  • Troponin C — is a part of the troponin complex. It contains four calcium binding EF hands. It contains an N lobe and a C lobe. The C lobe serves a structural purpose and binds to the N domain of TnI. The C lobe can bind either Ca2+ or Mg2+. The N lobe, which… …   Wikipedia

  • Troponin — Troponin, globuläres Protein in den Actinfilamenten der ⇒ Myofilamente, das den miteinander verschlungenen Ketten aus F Actin jeweils im Abstand von 7 Actinmonomeren aufgelagert ist und das die ⇒ Tropomyosin Doppelhelix, die schraubig die… …   Deutsch wörterbuch der biologie

  • Troponin 1 — Skeletales (rot) Troponin Oberflächenmodell (T lila, I cyan, C grün) nach PDB  …   Deutsch Wikipedia

  • Troponin C — Skeletales (rot) Troponin Oberflächenmodell (T lila, I cyan, C grün) nach PDB  …   Deutsch Wikipedia

  • Troponin I — Skeletales (rot) Troponin Oberflächenmodell (T lila, I cyan, C grün) nach PDB  …   Deutsch Wikipedia

  • Troponin T — Skeletales (rot) Troponin Oberflächenmodell (T lila, I cyan, C grün) nach PDB  …   Deutsch Wikipedia

  • Troponin — Übergeordnet Mikrofilament Untergeordnet Kardiales Troponin Rotes skelettales Troponin Weißes ske …   Deutsch Wikipedia

  • troponin — Complex of three proteins, troponins C, I, and T, associated with tropomyosin and actin on the thin filament of striated muscle, upon which it confers calcium sensitivity. There is one troponin complex per tropomyosin. Troponin C (18 kD) binds… …   Dictionary of molecular biology

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