trimethoprim-sulfamethoxazole

trimethoprim-sulfamethoxazole
A drug combination consisting of a dihydrofolate reductase inhibitor (trimethoprim) and a sulfonamide antibacterial drug (sulfamethoxazole). The drug combination is synergistic as the drugs interfere with two successive steps in the formation/utilization of folic acid by microorganisms. Used to treat many infectious diseases.

Medical dictionary. 2011.

Игры ⚽ Нужно решить контрольную?

Look at other dictionaries:

  • Trimethoprim/sulfamethoxazole — Combination of Trimethoprim Dihydrofolate reductase inhibitor (16.7%) Sulfamethoxazole Sulfonamide antibiotic (83.3%) …   Wikipedia

  • trimethoprim-sulfamethoxazole — noun A combination of trimethoprim and sulfamethoxazole in the ratio of 1 to 5. Syn: TMP SMX, co trimoxazole …   Wiktionary

  • trimethoprim-sulfamethoxazole — An antibiotic drug used to treat infection and prevent pneumocystis carinii pneumonia …   English dictionary of cancer terms

  • Sulfamethoxazole — Systematic (IUPAC) name 4 amino N (5 methylisoxazo …   Wikipedia

  • Trimethoprim — Systematic (IUPAC) name …   Wikipedia

  • trimethoprim — An antimicrobial agent that potentiates the effect of sulfonamides and sulfones; usually used in combination with sulfamethoxazole. * * * tri·meth·o·prim trī meth ə .prim n a synthetic antibacterial drug C14H18N4O3 used alone esp. to treat… …   Medical dictionary

  • sulfamethoxazole — A sulfonamide related chemically to sulfisoxazole, with a similar antibacterial spectrum, but a slower rate of absorption from the gastrointestinal tract and urinary excretion. * * * sul·fa·meth·ox·a·zole or chiefly Brit sul·pha·meth·ox·a·zole… …   Medical dictionary

  • trimethoprim — n. an antibacterial drug that is active against a range of microorganisms; taken by mouth, it is used mainly in the treatment of chronic urinary tract infections and respiratory tract infections. Long term treatment may cause anaemia due to… …   The new mediacal dictionary

  • sulfamethoxazole — noun Etymology: sulfa + methyl + oxazole, a compound C3H3NO (from International Scientific Vocabulary ox + azole) Date: 1960 an antibacterial sulfonamide C10H11N3O3S used alone or in combination with trimethoprim (as in the treatment of urinary… …   New Collegiate Dictionary

  • trimethoprim — noun Etymology: tri + meth + prim (by shortening & alteration from pyrimidine) Date: 1964 a synthetic antibacterial and antimalarial drug C14H18N4O3 used alone or in combination with sulfamethoxazole …   New Collegiate Dictionary

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”