titin

titin
A very large fibrous protein that connects thick myosin filaments to Z discs in the sarcomere.

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ti·tin (tiґtin) an extremely large (about 3000 kDa), flexible polypeptide that occurs in striated muscle, spanning half the length of a sarcomere, and serves as a scaffold to which myofibrils and other muscle-related proteins are attached, also providing elasticity by connecting the ends of the thick filaments to the Z band. It is activated by phosphorylation and by calmodulin binding, facilitates assembly of the sarcomere by providing defined binding sites for other sarcomeric proteins, and has kinase activity. Called also connectin.

Medical dictionary. 2011.

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Look at other dictionaries:

  • Titin — The three dimensional structure of a type I module from titin. PDB rendering based on 1bpv …   Wikipedia

  • Titin — Struktur nach PDB 1bpv …   Deutsch Wikipedia

  • Titin — Ti|tin [nach den Titanen, dem zweiten, von Zeus gestürzten Göttergeschlecht (wegen der Abmessungen); ↑ in (3)], das; s: im Muskelgewebe ein kontraktiles Strukturprotein ungewöhnlicher Länge (MG ca. 3 · 106), das die Myosinfibrillen verbindet. * * …   Universal-Lexikon

  • titin — (= connectin) Family of enormous proteins (2000 3500 kD) found in the sarcomere of striated muscle. Form a scaffolding of elastic fibres that may be important for correct assembly of the sarcomere. Each titin molecule spans from M line to Z disc …   Dictionary of molecular biology

  • Titin de Martigues — Titin des Martigues Titin des Martigues est un film français réalisé par René Pujol et sorti en 1938. Sommaire 1 Synopsis 2 Commentaire 3 Fiche technique 4 Distribution …   Wikipédia en Français

  • Titin des martigues — est un film français réalisé par René Pujol et sorti en 1938. Sommaire 1 Synopsis 2 Commentaire 3 Fiche technique 4 Distribution …   Wikipédia en Français

  • Titin des Martigues — est un film français réalisé par René Pujol et sorti en 1938. Sommaire 1 Synopsis 2 Fiche technique 3 Distribution 4 Liens externes …   Wikipédia en Français

  • titin — noun A protein important in the contraction of striated muscle tissues …   Wiktionary

  • TITIN — Titinia, Titinius …   Abbreviations in Latin Inscriptions

  • Augusto Ibáñez Sacristán — Titín III Nombre completo: Augusto Ibáñez Sacristán Fecha de nacimiento: 13 de enero de 1969 (42 años) Lugar de nacimiento: Tricio, La …   Wikipedia Español

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