terfenadine

terfenadine
An H1 antihistamine used to treat a variety of allergic conditions; has fewer sedative effects than other antihistamines, but in combination with several other drugs may cause serious cardiac arrhythmias.

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ter·fen·a·dine (.)tər-'fen-ə-.dēn n a drug C32H41NO2 formerly used as a nonsedating antihistamine but now withdrawn from U.S. markets because of its link to cardiac arrhythmias see SELDANE

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n.
an antihistamine used for the treatment of the symptoms of hay fever, such as sneezing, itching, and watering of the eyes, and urticaria. It is administered by mouth; commonest side-effects are drowsiness, headache, and gastrointestinal upsets.

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ter·fen·a·dine (tər-fenґə-dēn) a nonsedating antihistamine (H1 receptor antagonist) formerly used in the treatment of allergic conditions but withdrawn in the United States because of possible cardiotoxic effects.

Medical dictionary. 2011.

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  • Terfenadine — Systematic (IUPAC) name (RS) 1 (4 tert butylphenyl) 4 {4 [hydroxy(diphenyl)methyl]piperidin 1 yl} butan 1 ol Clinical data AHFS/ …   Wikipedia

  • terfenadine — /tûr fenˈə dēn/ noun An antihistamine drug used in the treatment of hay fever …   Useful english dictionary

  • terfenadine — noun An antihistamine drug formerly used to treat allergic conditions, superseded by fexofenadine in the 1990s due to the risk of cardiac arrhythmia …   Wiktionary

  • terfénadine —  n.f. Médicament antiallergique …   Le dictionnaire des mots absents des autres dictionnaires

  • Терфенадин (Terfenadine) — антигистаминный препарат; применяется для лечения сенной лихорадки и устранения ее проявлений (чиханье, зуд и слезотечение).Назначается внутрь; возможные побочные эффекты: сонливость, головные боли и нарушения деятельности желудочно кишечного… …   Медицинские термины

  • ТЕРФЕНАДИН — (terfenadine) антигистаминный препарат; применяется для лечения сенной лихорадки и устранения ее проявлений (чиханье, зуд и слезотечение).Назначается внутрь; возможные побочные эффекты: сонливость, головные боли и нарушения деятельности желудочно …   Толковый словарь по медицине

  • H1 antagonist — An H1 antagonist is a histamine antagonist of the H1 receptor that serves to reduce or eliminate effects mediated by histamine, an endogenous chemical mediator released during allergic reactions. Agents where the main therapeutic effect is… …   Wikipedia

  • Fexofenadine — Drugbox IUPAC name = 2 [4 [1 hydroxy 4 [4 (hydroxy diphenyl methyl) 1 piperidyl] butyl] phenyl] 2 methyl propanoic acid width= 200px CAS number= 153439 40 8 ATC prefix= R06 ATC suffix= A626 ATC supplemental= PubChem= 3348 DrugBank= APRD00349 C=32 …   Wikipedia

  • CYP3A4 — Cytochrome P450, family 3, subfamily A, polypeptide 4 Structure of CYP3A4 (from PDB 1W0E). Heme group visible at center …   Wikipedia

  • Astemizole — Systematic (IUPAC) name 1 [(4 fluorophenyl)methyl] N [1 [2 (4 methoxyphenyl)ethyl] 4 piperidyl]benzoimidazol 2 amine Clinical data AHFS/ …   Wikipedia

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