Launois-Bensaude syndrome

Launois-Bensaude syndrome
A disorder characterized by painless symmetrical diffuse deposits of fat beneath the skin of the neck, upper trunk, arms and legs. The condition is thought to be genetic although its exact mode of inheritance is uncertain; it may be a mitochondrial DNA disease. It frequently appears in association with alcoholic liver disease, macrocytic anemia ("low blood" with big red blood cells) and peripheral neuropathy (disease of the peripheral nervous system, as opposed to the brain and spinal cord). The peripheral neuropathy has often been laid to alcoholism, but the neuropathy is likely an integral part of the syndrome. This disorder affects mainly men and is more frequent in the Mediterranean area. It has been suggested that the distribution of fat in this disease resembles that of a pre-Roman (6th century BC) Italic statue called the Capestrano warrior discovered in the Abruzzi region of Italy. The syndrome is also known as multiple symmetrical lipomatosis, cephalothoracic lipodystrophy, and Madelung disease. It was called 'fat neck' (Fetthals) by Madelung in 1888.

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Lau·nois-Ben·saude syndrome (lo-nwahґ bah-sōdґ) [P.-E. Launois; Raoul Bensaude, French physician, 1866–1938] multiple symmetric lipomatosis; see under lipomatosis.

Medical dictionary. 2011.

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  • syndrome — The aggregate of symptoms and signs associated with any morbid process, and constituting together the picture of the disease. SEE ALSO: disease. [G. s., a running together, tumultuous concourse; (in med.) a concurrence of symptoms, fr. syn,… …   Medical dictionary

  • Launois — Pierre E., French physician, 1856–1914. See L. Cléret syndrome, L. Bensaude syndrome …   Medical dictionary

  • Raoul Bensaude — (1866 October 25, 1938) was a French physician who practiced medicine in Paris. He is known for his work with Emile Charles Achard (1860 1944) involving the description of paratyphoid fever and isolation of the bacillus, Salmonella paratyphi B .… …   Wikipedia

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  • Madelung disease — A disorder characterized by painless symmetrical diffuse deposits of fat beneath the skin of the neck, upper trunk, arms and legs. The condition is thought to be genetic although its exact mode of inheritance is uncertain; it may be a… …   Medical dictionary

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  • Lipomatosis, multiple symmetric — A disorder characterized by painless symmetrical diffuse deposits of fat beneath the skin of the neck, upper trunk, arms and legs. The condition is thought to be genetic although its exact mode of inheritance is uncertain. It may be a… …   Medical dictionary

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